Pranav Sharma

Founder and Chief Executive Officer at Xosomix

Role: Founder and Chief Executive Officer at Xosomix
Location: San Diego, CA, US
LinkedIn followers: 500 followers

General Business & ManagementView LinkedIn profile

About Pranav Sharma

Neuroscientist and cell biologist, who has used multi-disciplinary tools to understand neuronal plasticity and bring novel approach to understanding and therapy of Rett Syndrome and Autism Spectrum Disorders. A proven problem solver with experience of conception and successful execution of a major multi-institute collaboration. A team player with passion for learning and quest for improving human health.

Experience

Founder and Chief Executive Officer
Xosomix
Oct 2020 — Present · San Diego County, CA, US

Education

Jawahar Lal Nehru University
Master's of Science, Biotechnology
National Center for Biological Sciences, Bangalore
Doctor of Philosophy (Ph.D.), Cell Biology and Biophysics
Tata Institute of Fundamental Research, Mumbai
Doctor of Philosophy (Ph.D.), Cell Biology and Biophysics

Contact information

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Work email
s•••••@xosomix.com
Personal email
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Current company

Xosomix

Biotechnology Research · 2 employees · Founded 2020 · San Diego, California, United States

Xosomix (pronounced as \"exosomix\") is a biotechnology company involved in the development of the next generation therapeutics using exosomes. Xosomix is founded on the preclinical research demonstrating the first therapeutic use of exosomes in a brain disorder, Rett Syndrome. Problem: About 20% of the U.S. population suffers from a diagnosable mental illness. Brain disorder therapeutics is ~$100B market with just 50% patient reach and poised to grow at a rapid rate. Despite huge market and unmet need, the drugs targeting brain disorders range from ineffective to partially effective and treat symptoms rather than altering the course of disease. In addition, early diagnosis of neurological disorders remains a challenge and severely limits the window and scope of intervention for the development of therapeutics. Solution: Exosomes are transportation logistics services of the body that can cross blood-brain barrier to carry biomolecules to specific cellular targets and have capability to heal the defective cells and tissues. Exosomes play a fundamental role in the neural circuit development. Exosomes are part of endolysosomal system and are emerging as a key player in the progression of neurodegenerative disorders. Their therapeutic potential has been demonstrated in pre-clinical models of stroke and Rett Syndrome, a neurodevelopmental disorder with autism like symptoms. We will harness the brain delivery capability of exosomes to enable use drugs that failed due to poor penetration and increase the efficacy of existing drugs. We will use state of the art proteomic platform to discover the early biomarkers of neurological disorders on CNS-derived exosomes from the blood. We will harness the healing capability of exosomes to usher the next generation of therapeutics for brain disorders.

xosomix.com

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About Pranav Sharma

Experience

Founder and Chief Executive Officer

Education

Jawahar Lal Nehru University

National Center for Biological Sciences, Bangalore

Tata Institute of Fundamental Research, Mumbai

Find verified contacts for anyone on LinkedIn