Devin Porter
Functional Genomics | Single-Cell Multiomics | Drug Discovery
- Role
- Senior Scientist - Functional Genomics at Champions Oncology, Inc.
- Location
- Rockville, MD, US
- LinkedIn followers
- 500 followers
Experience
Senior Scientist - Functional Genomics
May 2025 — Present · Rockville, MD, US
Develop and optimize DRUG-seq workflows: Implement high-throughput, cost-effective bulk RNA sequencing methods to generate transcriptome-wide profiles from compound- and siRNA-treated organoid cultures, elucidating mechanisms of action and off-target effects.• Perform treatments on PDX-derived organoid (PDXO) models: Utilize patient-derived organoid cultures that preserve tumor genomics and drug sensitivity, serving as predictive platforms for functional screening.• Analyze gene-expression and Functional data: Interpret transcriptomic datasets from DRUG-seq assays to inform early-stage drug discovery efforts, including compound prioritization, biomarker identification, and mechanistic insights.
Skills
- Powerpoint
- Microsoft Excel
- Uv/Vis
- Dna Methylation
- Affinity Chromatography
- Ir Spectroscopy
- Teamwork
- Protein-Dna Interaction Assay
- Facs Analysis
- Enzyme Kinetics
- Ucsc Genome Browser
- Microsoft Word
- Public Speaking
- Methylation Specific High Resolution Melt Analysis
- Bisulfite Specific Amplicon Sequencing
- Illumina's Nextera Xt Dna Library Preparation Kit
- Ficoll-Gradient Mononuclear Cell Isolation
- Single Cell Rna-Seq
- Dna/Rna/Protein Extraction
- Peptide Kinetic Assays
- Bioinformatic Analysis
- Handling Human Blood Samples
- Cell Viability Assays
- Circular Dichroism
- Troubleshooting
- Chip-Seq
- In Vitro Diagnostic Development
- Protein Purification
- Epigenetics
- Graphpad Prism
- Library Preparation
- Atac-Seq
- Brain Organoids
- Gro-Seq
- Qrt-Pcr
- Eukaryotic Cell Culture
- Nanostring Ncounter Analysis System
- Immunomagnetic-Bead Isolations
- Data Analysis
- Chromosome Capture Conformation (3c-Seq)
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