Phillip Smethurst
Senior Scientist @MSD
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WORK HISTORY
Senior Scientist @MSD
EDUCATION
UCL
Master of Science (MSc), Clinical Neuroscience
University of Portsmouth
Bachelor of Science (BSc), Biomedical Sciences, General
UCL
Doctor of Philosophy (PhD), Molecular Neuroscience
SKILLS
ABOUT PHILLIP SMETHURST
Translational neuroscientist with 15+ years’ experience in neurodegenerative disease biology and early drug discovery, adding value through scientific judgement, programme-level thinking, and ownership of decision-ready datasets that inform programme prioritisation and progression within cross-functional teams.My background spans human-relevant disease models, target validation, and proteinopathy-driven mechanisms linked to cellular proteostasis, with experience shaping early discovery and translational decisions in pharma-based discovery programmes.Looking ahead, I’m focused on translational science, discovery strategy, and external innovation roles, alongside developing a venture-first thesis broadly centred on coordinated tuning of protein degradation pathways in neurodegeneration.I’m also an experienced, self-taught pianist and contemporary classical composer, and I value the overlap between scientific and musical thinking — structure, pattern, and creative iteration.
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