Pete Dragovich

About Pete Dragovich

Record of identifying multiple promising small-molecule therapeutic agents which demonstrate efficacy and acceptable safety in human clinical trials. – Excellent knowledge of oncology, immunology/inflammation, and antiviral therapeutic areas. – Working knowledge of antibacterial and CNS therapeutic areas. – Expert in applying modern medicinal chemistry principles to the identification, optimization, and development of small-molecule therapeutic agents. Examples include: structure-based design, fragment-based design, and property-based design. inhaled delivery (lung-targeted therapeutics). – Highly familiar with technologies and activities associated with all Discovery and Development stages from target identification through phase II clinical trials. • Versatile leadership capabilities. – Ability to effectively lead large or small organizations or groups (up to ca. 100 individuals). – Extensive project leadership, coordination, and management experience. – Ability to coordinate external contractors.• Extensive experience with the synthesis and scale-up of small-molecule drug candidates. – Kinase inhibitors, epigenetic modifiers, effectors of protein homeostasis (degraders). – Macrocyclic peptides, peptide mimetics, nucleosides, other heterocycles. – Chiral compounds. – Combinatorial/parallel chemistry. – Development of synthetic processes suitable for kg-scale applications. – Execution of multi-kg scale-up campaigns (GMP and non-GMP).• Highly familiar with the design, synthesis, and characterization of antibody-drug conjugates (ADCs), chimeric protein degraders (PROTACs), and PROTAC-antibody conjugates.• Author or co-author of many peer-reviewed scientific publications (>100) and and review articles (5).• Inventor or co-inventor of >50 issued US patents and pending patent applications.Specialties: Pharmaceutical research, drug discovery and development, medicinal chemistry, organic chemistry, project leadership and management, department supervision and management

Experience

1. Principal Fellow

   Genentech

   Aug 2023 — Present · South San Francisco, CA, US

Education

• Caltech

  PhD, Chemistry

  1988 — 1993

• University of California, Berkeley

  BS, Chemistry

  1984 — 1988

Skills

• Chemistry
• Drug Discovery
• Organic Synthesis
• Biotechnology
• Kinases
• Oncology
• Ind
• Biomarker Discovery
• Lc-Ms
• Life Sciences
• Drug Design
• Gmp
• Drug Development
• Antiviral
• Immunology
• Pharmaceutical Industry
• Pharmaceutical Research
• Medicinal Chemistry
• Lead Change
• Clinical Trials
• Organic Chemistry