Pernille Marie Madsen
Senior Scientist i, Genetic and Metabolic Disease @Beam Therapeutics
Signup · Get unlimited contacts
WORK HISTORY
Senior Scientist i, Genetic and Metabolic Disease @Beam Therapeutics
Led multiple discovery-stage gene editing assets, generating decision-driving datasets that de-risked preclinical programs and supported IND-enabling strategy while expanding platform reach beyond base and prime editing to larger patient populations.• Built high-impact assay and cell model platforms that accelerated timelines by months and scaled screening throughput across the portfolio.• Advanced a first-in-class multiplex liver editing strategy and identified lead candidates for a high-prevalence disease through rigorous translational and competitive diligence.• Drove portfolio strategy by integrating biological feasibility, competitive landscape analysis, and KOL insight into actionable asset prioritization.• Partnered with BD to evaluate next-generation technologies and external licensing opportunities, serving as internal CNS subject matter expert and guiding platform expansion.
EDUCATION
Syddansk Universitet - University of Southern Denmark
Master of Science (M.Sc.), Biomedicine
Syddansk Universitet - University of Southern Denmark
Bachelor of Science (B.Sc.), Biomedicine
University of Miami Miller School of Medicine
Visiting Student at The Miami Project to Cure Paralysis, Neuroscience
Syddansk Universitet - University of Southern Denmark
Ph.D. Candidate, Neuroscience
ABOUT PERNILLE MARIE MADSEN
PhD-trained translational neuroscientist with deep expertise in CNS and rare disease biotechnology and drug discovery. Specialized in glial biology, gene therapies, and rare metabolic disorders, with hands-on experience in iPSC disease modeling, base and prime editing, and in vivo CNS models. Proven track record in scientific diligence, competitive landscape analysis, and data-driven go/no-go decision-making across startup and biotech environments. Collaborative leader who partners effectively with R&D, business development, and KOLs to drive portfolio strategy and investment decisions. Driven by a passion to translate innovative science into meaningful therapies for patients.
This profile is compiled from publicly available professional sources. Unifers is not affiliated with or endorsed by LinkedIn. Request removal of this profile.