Pavimol Angsantikul

About Pavimol Angsantikul

I am a pharmaceutical development scientist and formulation lab head of the Angsantikul Laboratory at the Population Council, a global non-profit organization that conducts research and develops solutions to improve sexual and reproductive health and rights. With over 10 years of experience in pharmaceutical science and biomedical engineering, I have established a formulation laboratory that conducts preclinical and early clinical biological drug product development for sexual and reproductive health interventions, following GxP and ICH guidelines. I serve as drug product lead and collaborate with analytical, preclinical, and RAQA teams to underpin in vitro and in vivo safety, PK/PD studies, and regulatory submissions. My core competencies include pre-formulation, formulation, characterization, manufacturing, and stability of novel biological formulations following ICH guidelines and the design and coordination of preclinical studies. I also have expertise in biomimetic nanomedicine, mucosal tissue interfacing, and integration of nano/micro-scale and macro-scale drug delivery systems. My mission is to apply engineering designs to develop innovative and effective delivery systems that address unmet needs and challenges in pressing global health.

Experience

1. Pharmaceutical Development Scientist and Formulation Lab Head

   Population Council

   Sep 2020 — Present

   Established a new formulation team and supported people development to advance biologics drug products through preclinical and early clinical development.• Built and led a team to conduct pre-formulation, formulation, and characterization of novel biological formulations• Designed manufacturing process for tray lyophilization to achieve targeted product attributes• Designed and led stability studies of biological drug products following ICH guidelines• Collaborated with analytical team to develop and validate UPLC method for biological drug substance and drug product• Coordinated with preclinical teams to provide biological drug products for in vitro and in vivo safety, PK/PD studies• Regularly communicated with RAQA team to ensure smooth translation of drug products to early clinical stage• Authored and reviewed regulatory and technical documents, study reports, and manuscripts

Education

• Chulalongkorn University

  Bachelor's degree, Nano Engineering

  2008 — 2012

• UC San Diego

  Doctor of Philosophy - PhD, NanoEngineering

  2013 — 2018

• Harvard University

  Postdoctoral Research Fellow, Bioengineering and Biomedical Engineering

  2018 — 2020