Paul Gillespie

About Paul Gillespie

Contributed to 5 clinical candidatesLed teams of up to 25 chemists, with a focus on developing skills and building on strengthsBuilt hit-to-lead group that handled more than 50 HTS campaignsMedicinal chemist on more than 30 due diligencesExtensive experience working with CROs on synthesis, assays, DMPK and efficacyExperience with CADD, SBDD, AI/ML models, genererative models, cheminformatics and DELProposed 4 new targets45 patents35 publicationsMultilingual

Experience

1. Medicinal Chemistry Leader

   Flutterby Consultants Inc

   Oct 2025 — Present · San Francisco, CA, US

   The mission of Flutterby Consultants is to help our clients navigate the drug discovery process from target selection to IND submission, with a focus on medicinal chemistryWe have expertise in the following areas:StrategyWorking with Contract Research Organizations (CROs)Hit IdentificationLead IdentificationLead OptimizationIntellectual Property from a scientific perspectiveFor an initial consultation, please contact us by email at i•••@flutterby.ai

Education

• Trinity College Dublin

  Master of Science (M.Sc.), Chemistry

  1986 — 1988

• Trinity College Dublin

  B.A. (Mod.), Chemistry

  1982 — 1986

• Princeton University

  Doctor of Philosophy (PhD), Organic Chemistry

  1988 — 1991

Skills

• Scientific Writing
• Chemistry
• Drug Discovery
• Organic Synthesis
• Organic Chemistry
• Patents
• Biochemistry
• Translational Medicine
• Adme
• High Throughput Screening
• Pharmaceutical Industry
• Peptides
• Lc-Ms
• Scifinder
• Life Sciences
• Small Molecules
• Target Identification
• Biotechnology
• Molecular Modeling
• Drug Development
• Cheminformatics
• Drug Design
• Nmr
• Pharmaceutical Research
• Medicinal Chemistry
• Heterocyclic Chemistry
• Lead Change
• Drug Metabolism
• Clinical Development
• Computational Chemistry
• Biomarkers
• Dmpk
• Synthetic Organic Chemistry
• Pharmacology
• Oncology