Om Prakash Sharma
Head of Bioinformatics @Natiggs Gmbh
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WORK HISTORY
Head of Bioinformatics @Natiggs Gmbh
Baden-Württemberg, DE
Designed and implemented three AI-based models for antibody design and optimization, enabling rapid in-silico exploration of candidate therapeutics. Built an automated pipeline to screen large-scale antibody sequence libraries for desirable structural and functional properties. Developed a high-throughput interaction evaluation pipeline capable of assessing millions of antibody–antigen binding combinations efficiently. Created proprietary Antibody Prioritization Guidelines using curated datasets, improving decision-making in candidate selection workflows. Engineered an AI-powered tool for B-cell sequence-to-structure prediction, accelerating early-stage antibody design from sequence data.
EDUCATION
Maharaja Ranjit Singh College of Professional Sciences, Hemkunt Campus, Village Palda, Khandwa Road, Indore-452017
B.Sc, Biomathematics, Bioinformatics, and Computational Biology
Periyar University
Master's degree, Bioinforamatics
Pondicherry University
Doctor of Philosophy (Ph.D.), Bioinformatics
ABOUT OM PRAKASH SHARMA
I am a seasoned professional with 15+ years of invaluable experience in Bioinformatics and Data Science, with over 6+ years of leadership roles. My career has been defined by pioneering innovation and driving impactful change:Established a cutting-edge Bioinformatics and Innovation Center at Innoplexus AG, where I led the development of advanced learning models to address intricate bioinformatics and drug discovery challenges. Our initiatives resulted in the successful launch of new business units and services, strategically aligned with P&L and corporate objectives.My leadership extended to overseeing high-performance teams specializing in AI and life sciences, making substantial contributions to Research & Development. Leveraging Python for automation, we achieved significant breakthroughs in AI-based Drug Repurposing, Biomarker Discovery, Antibody Optimization, Drug Combinations, Target Identification, and Indication Prioritization.My skill set encompasses proficiency in Python, MongoDB, Data Science, and Generative AI, complemented by strong competencies in Product Management, Program Management, Business Development, and Project Management.Some of my career highlights include leading and executing Merck\'s MetAP2 Inhibitor Due Diligence program, which played a pivotal role in the acquisition of a valuable asset. I\'ve successfully managed and executed over 10 pharmaceutical due diligence projects, facilitated more than 35 Drug Discovery and Partnership initiatives, secured multiple European Union (EU) funded grants, and completed over 20 fee-for-service projects.I am also a distinguished author with a portfolio of more than 20 peer-reviewed scientific articles and hold over 25 U.S. patents, reflecting my commitment to innovation and inventive prowess.I look forward to connecting with professionals who share a passion for life sciences, bioinformatics, and innovation.
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