Nikki Orth

About Nikki Orth

I am an innovative leader with over 25 years of experience in corporate finance complete with significant results in process improvement and driving change. I pay keen attention to detail, have exceptional analytical skills, and possess the ability to synthesize the most relevant points and see the big picture. My experience includes financial management, strategic planning, and information systems. I manage a full range of financial functions including month-end financial close, year-end financial close, financial reporting, financial planning, forecasting, cash management, financial analysis, financial modeling, fundraising, and identifying key investors and cost accounting. As a team player, I utilize cross-functionality and I am also able to help all of our team\'s operations, marketing, development, and legal aspects. Maintaining focus and the determination to stay on track is an integral part of my job. I assist fellow team members by helping them remove bottlenecks as well as focusing on the problem or solution instead of assigning blame to others.

Experience

1. Director of Operations and Finance

   2flo Ventures

   Nov 2025 — Present · Chicago, IL, US

   I serve as the Director of Operations at 2Flo Ventures, where I play a central role in supporting the firm’s Managing Partner and leadership team across operational strategy, investor relations, and financial coordination. Known for my exceptional attention to detail and organization, I can manage complex, fast-moving workstreams. At 2Flo, I oversee critical functions including fund and SPV administration, capital call execution, investor onboarding through Carta, internal and external communications, and coordination with legal, financial, and strategic partners. I manage accounting workflows, budgeting, QuickBooks reporting, and vendor relationships, ensuring accuracy, compliance, and clear financial visibility for leadership. With a strong background in financial operations, organization-wide systems management, and executive support, I am a trusted operational anchor for the firm. I am known for my integrity, responsiveness, and ability to anticipate needs.Responsibilities:• Lead operations, administration, and executive support for an early-stage healthcare venture capital firm.• Manage investor relations: capital calls, subscription documents, LP onboarding, SPVs, and communications.• Oversee fundraising workflows for Fund II and multiple SPV vehicles.• Coordinate legal, financial, and compliance processes with counsel and partners.• Manage QuickBooks accounting, class tracking, budgeting, AP/AR, and vendor payments.• Organize high-impact events and logistics, including conferences, investor meetings, and founder engagements.• Maintain internal systems, documentation, reporting, and firm-wide operational structure

Education

• DePaul University

  Bachelor's Degree, Computer Science/Network Technologies

  1998 — 2002

Skills

• Budgets
• Finance
• Payroll
• Cash Flow
• Employee Training
• Accounts Payable
• Data Entry
• Accounts Receivable
• Insurance
• Financial Reporting
• Financial Accounting
• Forecasting
• Recruiting
• Customer Service
• Policy
• Auditing
• Software Documentation
• Access
• Cash Management
• General Ledger
• Cost Accounting
• Accounting
• Management
• Mergers & Acquisitions