Neeraj Kapoor
Director Scientific Lead, Group a Strep and Periodontitis Vaccines @Vaxcyte
Signup · Get unlimited contacts
WORK HISTORY
Director Scientific Lead, Group a Strep and Periodontitis Vaccines @Vaxcyte
San Carlos, CA, US
Principal Investigator on CARB-X grant to lead IND-enabling studies for Group A Strep Vaccine program • Help facilitate pre-clinical / regulatory discussions across vaccine programs • Lead cross-functional efforts for helping transition programs from research to process development / cmc • Work closely with the senior leadership team for strategic discussions and opportunities for collaborations • Facilitate publication of research work conducted on upcoming vaccine programs within Vaxcyte
EDUCATION
Rockefeller University
Doctor of Philosophy (PhD), Biochemistry, Biophysics and Molecular Biology
Indian Institute of Technology, Kanpur
Master of science, chemistry
ABOUT NEERAJ KAPOOR
Specialties: • Design and Engineer chimeric Exosomes for targetted delivery of therapeutic payload • Conjugate Vaccines : Highly experienced in using chemistries for oxidizing / derivatizing antigenic polysaccharides for covalently attaching to carrier proteins for generating conjugate vaccine candidates • Protein Expression: Expert protein biochemist with more that 10 years of experience in generating proteins using both cell based (E.coli, Sf9, mammalian) or XpressCF+TM cell free protein synthesis systems. • Protein Purification: Purification using Affinity, HIC, Ion exchange, multi-mode and size exclusion chromatography on AKTA/FPLC (explorer / AVANT) • Carbohydrate and Cu2+-free click Chemistry : Anthrone Assay, BCA assay and free polysaccharide assays for generating conjugatable antigenic serotypes • Structural Biology and Biophysics: X-ray crystallography, NMR and Circular Dichroism analysis for secondary as well as tertiary protein structure determination. Protein-protein interaction techniques like Isothermal Titration Calorimetry, SEC-MALS and Fluorescence spectroscopy • Radiochemical assays: 3H-Thymidine incorporation for cell proliferation, 14C-Leucine for estimation of protein expression, 32P-ATP/GTP assay for measuring Kinase enzymatic activity • Molecular and cell biology: Experience and knowledge in recombinant DNA techniques to design expression vectors for a variety of proteins, Tissue culture, transient transfections, Retrovirus-mediated immortalization and protein expression, SDS-PAGE, ELISA, qRT-PCR, Western Blot, Immunoprecipitation, • Murine Models of Inflammation: K/BxN and LPS induced sepsis models followed by serum analysis • Microscopy: Transmission Electron Microscopy for analyzing • Computational Data Analysis: Microsoft office, Data analysis using Graph Pad Prism and Origin, Adobe Photoshop and illustrator CS6, ImageJ • Excellent written and verbal communication skills along with the ability to lead, manage and provide help while working in cross-functional project teams
This profile is compiled from publicly available professional sources. Unifers is not affiliated with or endorsed by LinkedIn. Request removal of this profile.