Nathan Guz

Head of Cmc @Calico Life Sciences

South San Francisco, CA, US
EMAILS
n•••@calicolabs.com
MOBILE NUMBERS
+16•••••••37

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WORK HISTORY

Apr 2025 — Present

Head of Cmc @Calico Life Sciences

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South San Francisco, CA, US

EDUCATION

2001 — 2003

University of Colorado Boulder

Post Doctoral, Organic Synthesis and Methodology

1997 — 2001

Colorado State University

Ph.D., Organic Chemistry

1992 — 1996

DePauw University

Bachelor of Arts - BA, Chemistry

1995 — 1996

University of Aberdeen

Modern European Languages

SKILLS

Organic ChemistryDrug DiscoveryOrganic SynthesisValidationHplcChemistryAnalytical ChemistryTechnology TransferDrug DevelopmentDesign of ExperimentsGmpProcess SimulationLife SciencesPharmaceutical IndustryQuality by Design

ABOUT NATHAN GUZ

Technical Operations and CMC Executive Leader with expertise across all aspects of small molecule drug substance, drug product, clinical supplies, and GMP quality in fast-paced biotech environments. A key process chemistry contributor to the marketed therapies Cometriq, Voxelotor, and Cotellic, with deep experience in small molecule chemical, formulation, and analytical development. Proven success in formulating diverse dosage forms, including tablets, capsules, parenteral, and intravitreal formulations. Skilled in developing phase-appropriate quality systems and IND-enabling CMC biologics programs, as well as managing corporate scientific partnerships. An accountable, results-driven leader who makes data-driven decisions to ensure success.

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