Natalie Bongiorno

Director of Research Operations @American Oncology Network

25+ years of leadership in Hematology/Oncology Clinical Research Operations, driving strategic andoperational excellence. Designed and built the research infrastructure and operational roles from the company\'s inception,laying the foundation for long-term success. Oversee and manage 90+ active Oncology/Hematology clinical trials simultaneously, ensuringseamless execution and regulatory compliance. Lead research in cutting-edge oncology treatments, including CAR-T, Bi-specifics, Antibody-DrugConjugates, and Precision Medicine, contributing to innovative drug development. Developed and scaled one of the largest and most successful community oncology researchprograms on the East Coast. Directed 600+ Hematology/Oncology clinical trials, overseeing clinical science, data management,and regulatory affairs to drive impactful patient outcomes. Expert in patient-centered clinical research, enhancing patient education, engagement, and trialparticipation strategies. Recognized Key Opinion Leader (KOL) in Clinical Research Operations, budget negotiations, andOncology/Hematology Clinical Trials. Achieved and exceeded key research metrics, including patient enrollment targets, whilenegotiating budgets and contracts to maximize financial sustainability. Spearheading AI-driven initiatives for clinical trial matching, leveraging molecular sequencing anddata aggregation for improved patient outcomes. Led practice growth initiatives, collaborating with cross-functional teams to expand researchcapabilities and optimize operational efficiencies. Ensure full compliance with NIH, GCP, SOPs, and FDA requirements, maintaining high standardsof quality, ethics, and regulatory adherence. Managed dual responsibilities as Director of Research Operations and Director of ClinicalOperations, driving both research strategy and clinical trial execution while ensuring synergy acrossclinical departments.