Narender Gavva

Head, Core Biology @Takeda

Los Angeles, CA, US
MOBILE NUMBERS
+19•••••••76

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WORK HISTORY

Sep 2017 — Present

Head, Core Biology @Takeda

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San Diego, CA, US

Leading a group of innovative functional/molecular genomics & human genetics scientists dedicated to augment the drug discovery pipeline with high quality target biology for Takeda core indications: Neuroscience, GI disorders, Immunology/Oncology, and Rare diseases. Group utilizes a broad array of cutting edge technologies in expression, regulation, human/patient genetics for TIDVAL & prioritization. Patient genetics follow up includes endogenous allelic expression imbalance, functional MOA discovery for risk and protective alleles, single cell/nuclei RNAseq from biopsies/post-mortem tissues, genome-wide CRISPR screens for target discovery including modifier allele discovery and synthetic lethality screens for additive/synergistic therapeutic MOAs.

EDUCATION

1987 — 1992

University of Hyderabad

Ph.D., life sciences, Received national scholarship from UGC and CSIR

1983 — 1986

Kakatiya University

M.Sc, Genetics, Received gold medal for University 1st rank in MS

ABOUT NARENDER GAVVA

Twenty plus years of “drug discovery” experience +recruiting/leading/mentoring innovative groups of scientists and projects. Pioneering utilization of functional genomics and human genetics in drug discovery. Deep expertise in full drug discovery cycle, TIDVAL to clinical teams. Strong record of planning, completing programs and delivering clinical candidates (e.g, AMG Led small molecule, antibody, and peptide programs). Contributed to research reports, patents, or IND and IBs. AMG 517, AMG AMG 747, AMG 334 gotta read recommendations from my mentors, colleagues, and team members (See

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