Mustafa Kamani

About Mustafa Kamani

Passionate scientist with a drive to develop innovative therapies • Experienced Leader of Discovery and Preclinical Research programs • 8 years industry experience as a Research Project Team Lead and Functional Areal Lead• 8 years experience designing, executing, and managing study externalization • Experience across multiple therapeutic modalities (Biologics, Gene Therapy, Oligonucleotide, Small Molecule)

Experience

1. Senior Scientist

   BioMarin Pharmaceutical Inc.

   Mar 2022 — Present

   Research Lead for high priority preclinical programs across multiple modalities (oligonucleotide, biologics, small molecule), driving preclinical strategy and advancing assets through key stage gates toward developmental candidates • Program Lead for BMN 355, a first-in-class monoclonal antibody targeting genetic arrhythmias; advanced the program from target validation through IND-enabling studies while compressing benchmark development timelines by 70% Inventor on international patent (WO20••••••26A1) covering compositions and methods for treating Long QT Syndrome • Originated and championed a small-molecule program with projected annual revenues >$1B, advancing it from concept to active preclinical development in half the company benchmark timeline with 1 FTE • Head of Externalization for Neuroscience in vivo studies, accountable for outsourcing strategy and execution across mouse, rat, rabbit, and NHP models at CROs and academic partners • Co-developed enterprise in vivo CRO evaluation standards, establishing rigorous scientific, operational, and ethical vetting criteria to ensure quality and compliance • Built and manage a global network of 15+ CROs across 6 countries, improving operational efficiency and reducing study turnaround times by up to 75% while maintaining high scientific and ethical standards • Anticipated and mitigated critical supply-chain risk by securing NHP capacity for 3 years during industry-wide shortages, ensuring uninterrupted execution of mission-critical studies across the portfolio • Influenced multiple Business Development decisions by designing and executing critical proof-of-principle experiments and providing expert scientific judgment, directly enabling licensing transactions • Recruited and led external Key Opinion Leaders, including a Nobel Laureate, to serve on scientific advisory committees, shaping program strategy and risk mitigation approaches

Education

• University of Toronto

  Ph.D, Biochemistry

  2013

• University of Toronto - University of Trinity College

  Hons. B.Sc, Biochemistry

  2003 — 2007

Skills

• Shrna
• In Vivo
• Thin-Layer Chromatography
• Column Chromatography
• Research
• Immunology
• Life Sciences
• Cell Biology
• Polymerase Chain Reaction (Pcr)
• Rnai
• Molecular Biology
• Fluorescence Microscopy
• Basic Organic Synthesis
• Data Analysis
• Tlc
• Chemistry
• Staff Supervision
• Protein Chemistry
• Dna Sequencing
• Writing
• Pcr
• Science
• Biochemistry
• Immunoprecipitation
• Organic Synthesis
• Western Blotting
• Teaching
• Cell Culture