Murugappan S.
Associate Director | Biophysics, Drug Discovery | Drug Hunter
- Role
- Associate Director at Kymera Therapeutics
- Location
- Boston, MA, US
- LinkedIn followers
- 500 followers
About Murugappan S.
As a Principal Scientist with 14+ years of expertise in biochemistry, biophysics, and molecular drug discovery, I lead cross-functional teams to advance transformative therapies targeting complex disease pathways. My experience spans the full spectrum of drug development, from early-stage target identification and mechanistic studies to lead optimization and preclinical validation.I excel in the design and execution of robust biochemical and biophysical assays, protein expression and characterization (including challenging soluble and membrane proteins), and the integration of cutting-edge technologies to enable structure-based drug design. I have a proven track record of managing multidisciplinary collaborations, overseeing CRO partnerships, and fostering innovation in both oncology and immunology programs.My scientific contributions are reflected in peer-reviewed publications and recognized by multiple research awards. I am passionate about leveraging advanced modalities and data-driven approaches to discover and develop novel therapeutics with real impact for patients.If you share an enthusiasm for bold scientific exploration—or are seeking to accelerate the translation of innovative science into new medicines—I\'d welcome a conversation.
Experience
Associate Director
Jan 2026 — Present
Education
University of Connecticut
Ph.D., Biochemistry, Biophysics and Molecular Biology
2011 — 2016
University of Connecticut
Masters, Biochemistry
2009 — 2011
Shanmugha Arts, Science, Technology and Research Academy
B.Tech, Biotechnology
2005 — 2009
Skills
- Akta
- Bioenergetics
- Sec-Mals
- Lipids
- Nanodiscs
- Structural Bioinformatics
- Biochemistry
- Radioactive Waste Management
- Protein Labeling
- Stopped-Flow Spectrometry
- Circular Dichroism
- Lipid Disorders
- Bn -Page
- Adobe Design Programs
- Fret
- Enzyme Kinetics
- Differential Scanning Calorimetry
- Spr
- Molecular Cloning
- Yeast Genetics
- Molecular Biology
- Radioactive Materials
- Protein-Lipid Interactions
- Protein Assays
- Agarose Gel Electrophoresis
- Liposomes
- Zeta Potential
- Isothermal Titration Calorimetry
- Dsf
- Research
- Statistics
- Mitochondria
- Affinity Chromatography
- R
- Protein Purification
- Matlab
- Enzyme Assays
- Gel Electrophoresis
- Spectrophotometry
- Tlc
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