Muruganandan Shanmugam
Senior Scientist, Neurology Research @Biogen
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WORK HISTORY
Senior Scientist, Neurology Research @Biogen
Cambridge, MA, US
EDUCATION
Madras Veterinary College
Doctor of Veterinary Medicine, Veterinary Sciences/Veterinary Clinical Sciences, General
Indian Veterinary Research Institute, Izatnagar
Doctor of Philosophy (Ph.D.), Pharmacology
Indian Veterinary Research Institute, Izatnagar
Master’s Degree, Pharmacology
SKILLS
ABOUT MURUGANANDAN SHANMUGAM
Neuroscientist at Biogen with a Doctor of Veterinary Medicine (DVM) and a Ph.D. in Medical and Health Sciences Research. Experience in diverse areas - Stem Cells & Regenerative Medicine (3D organotypic cultures to model degenerative diseases), Molecular Biology (Gene Cloning, viral gene delivery vector construction, siRNA, shRNA, CRISPR/Cas9 based gene editing), Proteomic Approaches (MSD, AlphaLISA, HTRF, WB, IF, IHC, IP), Gene Expression Analysis (High-Throughput Multiplex QPCR, ddPCR, RNAscope, NGS, scRNAseq, snRNAseq, Bulk RNA-Sequencing Analysis, Biomarker Discovery, Pathway Analysis), Gene Therapy, and Experimental Therapeutics. Expertise in designing experiments for high-throughput screenings and hands-on experience with the automated liquid handlers, workstations & robotic pipettors for high-throughput applications. An accomplished researcher with more than fifteen years of experience in pre-clinical drug development, and exploration and discovery of novel therapeutic targets to treat tissue degeneration associated with diabetes, cardiac & renal damage, immunological injury, cancer, osteoporosis, and inflammation. Identified new targets and therapeutic strategies using molecular and cell-based systems and as well as animal models for all these diseases. Proven leadership in both academic and industrial environments. Experience working in a fast-paced and collaborative environment. Expert in developing and managing SOPs, QC documents, and Tech transfer documents. Published more than 30 scientific articles, which have received more than citations. Prepared or participated in submitting grant applications to several agencies, including CIHR, NSHRF, NSERC, and Canadian Cancer Society.Previously, I worked as Research Associate & Lab Manager at Harvard University, where I investigated the therapeutic potential of targeting abnormal signaling pathways that disrupt the normal stem cell development to benefit patients suffering from skeletal tissue damage. Since 2022, I have focused my efforts on conducting research on novel therapeutic agents and preclinical drug development for neuromuscular disorders.I also have a strong interest in drug interactions, safety assessment, and clinical research, as well as public speaking. I am a lawful permanent resident in the United States.My professional &
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