Moumita Chakrabarti

Associate Scientist @Aragen Life Sciences

Hyderabad, IN

Assay development and screeningIndependently conducting all experimental procedures, performing data analysis, and preparing scientific presentations for internal reviews and external communicationsLeading a team of two direct reportees, overseeing experimental planning and execution to ensure timely and accurate delivery of project goals.Cell-based Assays:•Developed and optimized cellular HTRF, dual luciferase reporter, and multiplexed N-Luc/CTG assays in fibroblasts and engineered cancer cell lines for screening small molecule modulators and inhibitors (96- & 384-well formats).•Established AlphaLISA assays and HiBiT Lytic detection systems for quantifying endogenous protein levels and assessing PROTAC-induced degradation in cancer cell lines (384-well format).•Performed transient transfection and co-immunoprecipitation (co-IP) to study protein–protein interactions involving tumor suppressors in cancer models.Biochemical Assays:•Established fluorescence polarization (FP) competition assays to assess direct ligand binding with nuclear receptors (384-well format).•Conducted ligand displacement HTRF screening assays to evaluate compound binding and modulation of target proteins (384-well format).

University of Calcutta

M.Sc.

CSIR-Indian institute of chemical technology

Doctor of Philosophy - PhD

Scottish Church College (SCC)

Bachelor of Science - BS

St. Joseph's Convent

Class KG - XII