Monica Moulton
Director IT Project Management Office @X4 Pharmaceuticals
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WORK HISTORY
Director IT Project Management Office @X4 Pharmaceuticals
Boston, MA, US
Owned and managed the full enterprise IT budget ($11.7M → $5.4M), assuming expanded financial accountability during organizational transition and leadership restructuring- Led enterprise vendor strategy and contract governance; primary point of contact for MSPs and strategic IT partners, overseeing renewals, negotiations, performance management, and invoice approval- Senior IT strategy partner to executive leadership and COO, advising on capital allocation, investment prioritization, and cost optimization- Built and led the enterprise IT PMO, implementing structured intake, prioritization, KPI tracking, and governance processes across infrastructure, security, commercial, R&D, and G&A platforms- Designed and operationalized executive planning cadence (quarterly/annual prioritization, roadmap refresh, steering governance), improving on-time delivery by 20–30% and increasing decision velocity- Led IT Governance Committee operations, facilitating cross-functional investment reviews and enterprise-wide budget transparency- Served as IT business partner to R&D, Commercial, and G&A, aligning technology investment with business strategy and execution readiness.
EDUCATION
Universidad Centroamericana 'José Simeón Cañas'
Industrial Engineering
MIT Sloan School of Management
Executive Education, AI Strategy & Digital Transformation
ABOUT MONICA MOULTON
Enterprise IT PMO and Governance leader with a track record of building and scaling portfolio management functions within life sciences organizations. Partner to executive leadership on technology strategy, capital allocation, and delivery execution across infrastructure, security, commercial, R&D, and G&A platforms. Built and led enterprise PMOs from inception, implementing structured intake, prioritization, KPI reporting, and governance frameworks that increased delivery predictability and decision velocity. Experienced in portfolio and program management, budget ownership, vendor strategy, and operational transformation in regulated environments. Operate with full IT budget ownership and accountability, including CapEx/OpEx planning, contract governance, investment prioritization, and MSP/vendor oversight. Lead governance forums and executive reporting to ensure alignment between technology investments and business outcomes. Bilingual (English/Spanish). Focused on disciplined execution, financial rigor, and enterprise-wide impact. Chief of Staff | Senior Director, IT Strategy | Enterprise Program Leadership | Digital Execution
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