Mohosin Sarkar

Preclinical R&D Leadership | Innovative Protein & Antibody Engineer | Bi-/multispecific T Cell Engager Platform Development | ADC Engineering | Bioanalytical Sciences | CMC Developability Assessment | PK/PD/TK Evaluation

Role
Scientific Advisory Member at Voyant Bio
Location
New Haven, CT, US
LinkedIn followers
500 followers
Research & DevelopmentView LinkedIn profile

About Mohosin Sarkar

Highly innovative protein and antibody engineering executive with 15+ years of leadership experience across biotechnology and pharmaceutical R&D, specializing in the discovery, development, and translation of complex biologics. Deep expertise in bispecific and multispecific T-cell engager (TCE) platforms, antibody-drug conjugates (ADCs), bioanalytical sciences, and CMC-driven developability and regulatory readiness. Proven track record advancing programs from early discovery through IND-enabling milestones, with a strategic focus on oncology, immune cell biology, and immune-mediated disease.Throughout my career, I have built and led high-performing scientific teams and innovation programs, serving as inventor on 10+ patents and driving the development of differentiated, first-in-class biologics. My leadership emphasizes early technical and regulatory de-risking, CMC-compatible design, and scalable manufacturing strategies to accelerate timelines and maximize asset value. I bring deep experience in engineering and translating complex modalities, including Fc-fusion proteins, cytokine-integrated and costimulation-enabled T-cell engagers, and next-generation ADCs with advanced linker and payload chemistries.In my current role, I lead multidisciplinary R&D organizations focused on the creation of differentiated multispecific immunotherapies designed to deliver durable, selective immune modulation across hematologic malignancies, solid tumors, and autoimmune disease. My objective is to integrate scientific rigor, operational excellence, and strategic foresight to advance transformative therapies that address critical unmet medical needs and drive long-term organizational value.Core ExpertiseProtein & Antibody Engineering | Bispecific & Multispecific TCE Platforms | Biologics Discovery & Translation | ADC Design & Characterization | CMC Strategy & Developability | Bioanalytical Sciences | Immune Cell Biology | Scientific Leadership | IND-Enabling & Preclinical Development

Experience

  1. Scientific Advisory Member

    Voyant Bio

    Mar 2025 — Present

Education

  • University of Dhaka

    Bachelor of Science - BSc

  • The Ohio State University

    Doctor of Philosophy - PhD

    2004 — 2009

  • Kent State University

    Master of Science - MS

    2003 — 2004

Skills

  • Chemical Biology
  • Protein Chemistry
  • Molecular Biology
  • Elisa
  • Pcr
  • Cell Culture
  • Microsoft Excel
  • Solid Phase Synthesis
  • Microsoft Office
  • Cell
  • Microarray
  • Western Blotting
  • Research
  • Protein and Antibody Engineering
  • Immunoprecipitation
  • High-Performance Liquid Chromatography (Hplc)
  • Enzyme Kinetics
  • Immunohistochemistry
  • Hplc
  • Fplc
  • Protein Purification
  • Mass Spectrometry and Proteomics
  • High-Throughput Screening
  • Cell Biology
  • Cell Signaling
  • Chemistry
  • Facs
  • Immunology
  • Tissue Culture
  • Characterization
  • Teaching
  • Molecular Cloning
  • Biochemistry
  • Maldi-Tof
  • Small Molecule Combinatorial Library Design
  • Purification
  • Protein Expression

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