Mohammed Siddiquey
- Role
- Scientist, Viral Vector Process Development at Atara Biotherapeutics
- Location
- Thousand Oaks, CA, US
- LinkedIn followers
- 500 followers
About Mohammed Siddiquey
Vector process development scientist and virologist with a strong background in virology,…
Experience
Scientist, Viral Vector Process Development
Jun 2021 — Present · Thousand Oaks, CA, US
Directed multiple projects requiring broad skillsets:\\\\n\\\\nCell Line Development:\\\\n Providing technical and scientific leadership for engineering, selecting, extending, and cryopreserving retrovirus producer cell lines.\\\\n Generating high quality cell banks (MCB) and transferring MCB production process to GMP suites for CAR-T programs. Coordinating MCB safety and release test.\\\\n Authoring and reviewing process protocols/diagrams, technical reports, tech-transfer documents, IND reference documents, specifications, and CMC section of IND filings.\\\\n Serving as a SME for molecular virology, cell biology and genetics for CAR-T programs.\\\\n\\\\nUpstream Viral Vector Development:\\\\n Providing technical and scientific leadership for CAR-T upstream viral vector process development and characterization.\\\\n Thawing and extending vector producer cell lines and producing large scale viral vectors. Coordinating vector safety test and shipping vector materials to different functional groups.\\\\n Authoring and reviewing process protocols/diagrams, technical reports, tech-transfer documents, IND reference documents, specifications, and CMC section of IND filings.\\\\n Coordinating suspension adaptation and in-line filtration process.\\\\n Providing technical leadership for Adenoviral sequencing activity (NGS and sanger) for RCA detection and to establish program reference.\\\\n SME in planning new methods to detect EBV latency and improvements of vector design, epitope expression and APC system for T-cell stimulation.\\\\n\\\\nDownstream Viral Vector Development:\\\\n Providing technical and scientific leadership for CAR-T downstream viral vector process development and characterization.\\\\n Developing and characterizing tangential flow filtration (TFF) for retroviral vector.\\\\n Bags and bottles filling and control rate freezing of viral vector.\\\\n Authoring and reviewing process protocols/diagrams, technical reports, tech-transfer documents, IND reference documents, specifications, and CMC section of IND filings.\\\\n \\\\n\\\\n \\\\n \\\\n\\\\n \\\\n
Education
University of Chittagong
Bachelor's Degree, Microbiology, 3.62
2000 — 2004
Nagoya University Graduate School of Medicine
Doctor of Philosophy, Molecular Virology (Research Advisor: Hiroshi Kimura, MD, PhD), Grade A (Excellent)
2010 — 2014
University of Chittagong
Master's Degree, Microbiology, 3.77
2004 — 2005
Faridgonj, Chandpur, Bangladesh
HSC, Science
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