Mohammed Ibrahim

About Mohammed Ibrahim

Dedicated, focused and highly motivated principal scientist with exceptional knowledge…

Experience

1. Principal Scientist, Car-t (Cell Therapy) Analytical Development

   Bristol Myers Squibb

   Mar 2022 — Present

   Perform method development, qualification, regular testing and transfer (identity, strength/quantification, stability indicating), investigative analytical characterization and biophysical forensic support of cellular drug product, viral vector (e.g, lentiviral vector, AAV, and gene editing materials), customized raw materials/ancillary materials, excipients, process and formulation buffers using a variety of analytical technologies, such as spectroscopic methods (e.g, FT-IR and Raman), biophysical and forensic analytical characterization tools for particulate analysis (e.g, FlowCAM/Microscopic/Nanoparticle DLS analytics), and liquid and gas chromatography coupled with different detectors (e.g, UV/Fluorescence/CAD/MALS), GC-FID. • Partner with QC raw material, Process Development, Manufacturing Science and Technology, and Analytical Operation functions to analyze samples in Bio Safety Level-2 (BSL-2) lab environment, perform regular sample and investigational analysis activities, and transfer methods. • Develop and implement novel analytical technologies capable of characterizing vectors, raw materials/ancillary materials to improve understanding of critical process media, reagent, and buffer components. • Document experiments in an Electronic Lab Notebook (ELN). Author and review technical documents in an electronic document control system (e.g, Benchling and Veeva Quality Docs). • Participate in regulatory submissions and present data to peers and in cross-functional meetings. Publications: Chapter 7. Analytical Methods for In-Process Testing and Product Release, in \"Handbook of Cell and Gene Therapy: From Proof-of-Concept through Manufacturing to Commercialization\", CRC Press (2023)

Skills

• Research and Development (R&D)
• Organic Chemistry
• Nmr
• Spectroscopy
• Uv/Vis Spectroscopy
• Characterization
• Organic Synthesis
• Ir
• Chemistry
• Afm
• Nuclear Magnetic Resonance (Nmr)
• Biochemistry
• Ft-Raman
• Lc-Ms
• Nmr Spectroscopy
• Nanotechnology
• Gas Chromatography
• Analytical Chemistry
• Mass Spectrometry
• Fluorescence Spectroscopy
• Biophysics
• Validation
• Laboratory
• R&D
• Materials Science
• Infrared (Ir)
• Science
• Analytical Techniques
• Ir Spectroscopy
• Ftir
• Raman
• Fluorescence
• Uv/Vis
• Microscopy
• Gc-Ms
• Multivariate Analysis
• Raman Microscopy
• Surface Chemistry
• Confocal Microscopy
• Hplc