Mohammed Ghonime

About Mohammed Ghonime

Develop and advance IO programs from early development to proof-of-concept to IND filing and beyond - Experienced scientist with a strong background in Immunology, oncology, cancer immunotherapy and CAR T therapy- Manage multiple projects while adhering to aggressive timelines - Team leader and able to establish and leverage robust cross-functional relationships with key stakeholders across and beyond research in support of program goals - Experienced in Crispr/Cas9 gene editing of primary cells such as T cells- Experienced in identification of mechanism of action, resistance mechanisms, signaling pathways associated with antitumor drugs in in vitro and in vivo studies - Developed a new cell-based platform for adoptive immunotherapy by expansion of a subset of primary immune cells in vitro - Identified new drug leads by screening a panel of candidates in vitro and in vivo - Skilled in in development and execution of preclinical in vivo models- Skilled in in designing and executing cell-based functional assays - Skilled in immune cells phenotyping - Skilled in Immune cells purification by magnetic selection or FACS sorting and cultivation - Proficient in modern molecular and cellular biology techniques- Track record of independent thinking and achievements in immunology and oncology- Multitasker and lead multiple projects - Responsible for training and mentoring lab associates - Proficient in writing protocols, scientific proposals and IND reports - Perfect communication skills, strong interpersonal and team work skills - Problem solving and decision making skills with a sense of urgency - Highly motivated and enjoy working in fast-paced collaborative environment

Experience

1. Senior Scientist- Immunooncology Cell Therapy

   CRISPR Therapeutics

   Jan 2019 — Present · Cambridge, MA, US