Mingkuan Chen
Advancing Novel Immunotherapies
- Role
- Principal Scientist at Neurocrine Biosciences
- Location
- San Diego, CA, US
- LinkedIn followers
- 500 followers
About Mingkuan Chen
Experienced immunologist with a strong track record of advancing R&D-stage drug programs in autoimmunity and driving scientific discoveries in cancer immunotherapy and infection immunity. Proven success leading early discovery programs from target hypothesis through preclinical candidate (PCC) nomination, advancing programs through stage gates using a results-driven approach to generate robust, decision-enabling data packages aligned with key stakeholder needs. Deep expertise in molecule design, in vitro pharmacology, in vivo rodent efficacy models, PK/PD-driven strategy, and clinical data mining. Trusted cross-functional partner and people leader with extensive experience collaborating across protein engineering, lead optimization, DMPK, CMC, tox, translational, data science, clinical development, commercial, and regulatory functions, and leading internal teams and external CROs.
Experience
Principal Scientist
Feb 2026 — Present
Education
China Agricultural University
Bachelor's degree, Biology/Biological Sciences, General
2005 — 2009
University of Chinese Academy of Sciences
Ph.D., Microbiology
2009 — 2015
Skills
- Confocal Microscopy
- Dna
- Qpcr
- Rt-Pcr
- 定量聚合酶链式反应
- 细胞培养
- Genetics
- 蛋白质免疫印迹分析法
- 分子生物学
- Life Sciences
- Protein Expression
- Cell Culture
- Flow Cytometry
- Pcr
- 细胞生物学
- Cell Biology
- Protein Purification
- Molecular Biology
- 生物化学
- Molecular Cloning
- Western Blotting
- Biochemistry
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