Michael Doyle
Discovery Biotherapeutics Protein Science
- Role
- Director, Discovery Biotherapeutics Protein Science at Bristol Myers Squibb
- Location
- Princeton, NJ, US
- LinkedIn followers
- 500 followers
About Michael Doyle
SCIENTIFIC Advanced protein biophysical leader with over 80 publications on protein biophysical chemistry. Extensive expertise delineating biomolecular binding mechanisms using biophysical technologies (e.g, SPR, ITC, AUC, Thermal Stability Perturbation, Bio-Layer Interferometry, etc.). Recognized leader in protein binding and stability thermodynamics (Calorimetry Conference Young Scientist Award in Thermochemistry). Strategic use of multiple orthogonal bioanalytical technologies used to assess developability of protein therapeutic candidates. Hands-on experience with basic protein engineering (e.g, construct design strategies for optimal expression, isotype swapping of mAbs) and collaborative experience with computer-aided protein design experts on advanced protein engineering projects (e.g, humanization). STRATEGIC LEADERSHIP AND MANGEMENT Demonstrated experience strategically deploying biophysical binding and stability technologies to have maximum impact and efficiency, and to accelerate the discovery and optimization of protein therapeutic drugs from concept to early stage Development. Experienced in managing protein production and characterization priorities of a diverse portfolio of biologics (mAbs, fusion proteins, glycoproteins, Adnectins), small molecule targets, and many classes of protein reagents for structural and functional studies, across multiple therapeutic and geographic areas with broad organizational transparency and alignment. Proven line-management record of mentoring and developing high performing biophysical and protein purification leaders. Accomplished project team matrix leader that has delivered multiple mAb and non-mAb biologics candidates from early Discovery to early Development.
Experience
Director, Discovery Biotherapeutics Protein Science
Jul 2019 — Present · Princeton, NJ, US
Education
University of Colorado Boulder
Ph.D., Biophysical Chemistry
1982 — 1987
The Johns Hopkins University
Post-Doctoral, Biophysical Chemistry
1988 — 1989
Washington University School of Medicine in St. Louis
Post-Doctoral, Molecular Biophysics
1990 — 1992
Find verified contacts for anyone on LinkedIn
Unifers gives sales teams verified emails and direct dials, enriched profiles, and outreach that lands in the inbox.
Free plan included · No credit card required
This profile is compiled from publicly available professional sources. Unifers is not affiliated with or endorsed by LinkedIn. Request removal of this profile.