Melissa Rae Good

About Melissa Rae Good

I began my career at Merck, where my primary work had been the technology development and implementation of low-volume, high-throughput screening tools for antibody selection and media optimization, antigen and antibody expression and purification, undefined media characterization via DOE, and Ph1 program support. After transitioning to the gene therapy space in Upstream PD at Generation Bio, I led recombinant baculovirus optimization efforts to support Ph1 including cell line optimization, MCB generation, Ph1 BIICs-process optimization, PD/GMP tech transfer to multiple CMOs, and technical lead for GMP-BIICs generation.At CRISPR Therapeutics as the In Vivo Process Development team lead, I explored the challenges in the CGT space to manufacture mRNA, LNP, and rAAV, with a focus on platform development, GMP manufacturability, tech transfer, and technology development. I always welcome opportunities to learn new diverse skills and technology, and I work at a driven and upbeat pace.

Experience

1. Associate Director

   Dyne Therapeutics

   Apr 2025 — Present · Boston, MA, US

   CMC Biologics

Education

• The Johns Hopkins University

  M.S.E Chemical and Biomolecular Engineering, Cellular and Molecular Biotechnology

  2012 — 2013

• The Johns Hopkins University

  Bachelor of Science (B.S.), Chemical and Biomolecular Engineering

  2008 — 2012

Skills

• Guava Easycyte Ht
• Biochemistry
• Clone Selection
• Chemstation 11
• Confocal Microscopy
• Rp-Uplc
• Imola Randox
• Data Analysis
• Cedex Bioht
• Process Optimization
• Microsoft Office
• Organic Acids Analysis
• Cell Culture
• Molecular Biology
• Fluorescence Microscopy
• Matlab
• Hplc
• Microscopy
• Media Development
• Design of Experiments
• Cell Biology
• Protein Chemistry
• Nova Bioflex
• Empower 3
• Biotechnology
• Protein Purification
• Amino Acid Analysis
• Akta
• Ysi
• Statistics