Matthew Petrus
Scientist Ii @Eurofins Discovery
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WORK HISTORY
Scientist Ii @Eurofins Discovery
San Diego County, CA, US
Validate and optimize small scale assays to high-throughput screening (HTS) platform • Operate automated HTS robotic system, daily QC and troubleshoot technical issues • Responsible for all aspects of processing compounds• Design, validate and perform various in vitro and ex-vivo cell-based and biochemical assays to interrogate function of GPCRs and other drug targets • Perform assays addressing receptor/drug mechanism of action using targets expressing both recombinant as well as endogenous in native cells and tissues • Participate in automation and standardization of assays and creation of SOPs as needed • Perform and/or oversee SAR studies for small molecule drug optimization • Maintain familiarity with the relevant current scientific literature and provide scientific input both conceptually as well as to bring to bench internally novel experimental approaches and technologies • Participate in multiple drug discovery projects concurrently • Collect, analyze, and present experimental data summaries at team meetings internally and to outside collaborators and clients • Prepare written reports and SOPs • Read scientific literature and engage with project teams • Demonstrate an eagerness to train, mentor, and manage research associates. • Oversee team of associates
EDUCATION
Virginia Tech
MS
Radford University
Bachelor of Science (B.S.)
ABOUT MATTHEW PETRUS
At Takeda, my role has been instrumental in advancing drug discovery through the integration of high throughput screening and live-cell imaging technologies in immune-oncology and other fields. Our team\'s expertise in phenotyping and 3D cell culture has been pivotal for the development of innovative cell models that push the boundaries of disease understanding and treatment.Leveraging bioinformatic tools and chemotaxis analysis, we\'ve enhanced the precision of cell line selection and accelerated the identification of therapeutic targets. The collaborative spirit within our team has facilitated knowledge sharing, fostering an environment ripe for breakthroughs in RNA modalities and contributing significantly to Takeda\'s mission of pioneering novel healthcare solutions.
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