Matthew Jarvis
Principal Scientist, Target Discovery at Biosplice Therapeutics, Inc.
- Role
- Principal Scientist at Biosplice Therapeutics
- Location
- Minneapolis, MN, US
- LinkedIn followers
- 500 followers
About Matthew Jarvis
Highly motivated, independent, and critically thinking research scientist who synergizes bioinformatic and molecular biology techniques to study clinical cancer genomics and therapeutic development.
Experience
Principal Scientist
Jul 2023 — Present
Biosplice Therapeutics is developing first-in-class, small-molecule therapeutics based on pioneering science of alternative pre-mRNA splicing. Stemming from foundational discoveries in Wnt pathway modulation, Biosplice has elucidated novel biology linking CLK/DYRK kinases to the therapeutic regulation of alternative splicing. Alternative splicing is an essential biological mechanism that regulates the diversification of proteins in a cell, which, in turn, determines cell type and function. Biosplice’s target class governs the selection of tissue-specific mRNA splice sites, making them attractive, druggable targets within the cellular “command and control” center.Biosplice’s drugs in clinical development include lorecivivint for osteoarthritis (in Phase 3), cirtuvivint for numerous cancers, and a broad pipeline that ranges from Alzheimer’s disease to other degenerative conditions. Learn more at
Education
University of Minnesota Morris
Bachelor of Arts (BA), Biology, Psychology
2009 — 2013
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