Matthew Comienski

About Matthew Comienski

Working professional with 6+ years of experience supporting global oncology and hematology clinical trials within CRO environments. Proven track record managing $10M+ in investigator site payments, resolving complex reconciliation issues, and ensuring timely, accurate, and compliant financial execution across multi-study portfolios.I specialize in end-to-end clinical site payments, including investigator grants, payment reconciliation, forecasting, and issue resolution. I bring a strong process and controls mindset, with hands-on experience optimizing Medidata Payments workflows, developing SOPs and work instructions, and maintaining audit-ready financial operations in regulated environments.Known for operating with high ownership and sound judgment, I work closely with Clinical Operations, Finance, Accounts Payable, Legal, and external investigator sites to troubleshoot issues, improve transparency, and strengthen cross-functional alignment. I am comfortable navigating ambiguity, managing competing priorities, and independently driving solutions that improve accuracy, efficiency, and cycle times.

Experience

1. Clinical Site Payments Specialist

   Everest Clinical Research

   May 2023 — Present · NC, US

   Own end-to-end financial operations for four global oncology and hematology clinical trials, managing over $10M in investigator site payments year-to-date.Serve as primary point of contact for site payment execution, reconciliation, and issue resolution, ensuring timely, accurate, and compliant payments across multi-cycle study budgets.Analyze payment trends, variances, and discrepancies to proactively identify root causes, reducing outstanding liabilities and improving forecast accuracy.Implemented and optimized Medidata Payments workflows, standardizing processes and improving operational efficiency across study teams.Design and maintain Excel-based financial trackers supporting invoice processing, approval workflows, forecasting, and aging analysis to enhance financial visibility.Lead weekly sponsor-facing Investigator Grant calls, presenting payment status, addressing escalations, and aligning Finance and Clinical Operations stakeholders.Develop SOPs, tools, and internal guidance that strengthen compliance, reduce processing redundancies, and support audit readiness.Train cross-functional project teams on payment processes, reconciliation practices, and financial controls to ensure consistency across studies.

Education

• William Peace University

  Bachelor of Science, Business Analytics

  2015 — 2019