Mark Brundrett

Principal Architect - Strategy & Enterprise @AstraZeneca

Cambridge, GB
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WORK HISTORY

Mar 2020 — Present

Principal Architect - Strategy & Enterprise @AstraZeneca

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Cambridge, GB

Omics Platform Architect, focussed on defining and realising the vision for a collaborative platform to accelerate the speed from instrument to insights.• Conducted horizon scanning to stay abreast of emerging technologies and industry trends, driving continuous improvement and innovation.• Architected the pipelines to deliver FAIR data products to the research community.• Established Workflow as A Service to deliver repeatable, scalable, standards-based bioinformatics pipelines.• Selected potential solutions to deliver a highly scalable molecular data store to accommodate large-scale data requirements.• Fostered strong vendor relationships to leverage external expertise and technologies, ensuring the platform\'s effectiveness and efficiency.As Solutions Architect for the AI in Biologics Engineering initiative, architecting solutions to facilitate the researchers’ value stream from lead identification to lead optimisation. • Providing architecture support to scientists throughout the data lead optimisation process, leveraging machine learning techniques and MLOps-based architectureArchitected and delivered intelligent systems combining large language models with enterprise data platforms:• Designed agentic solutions for automated data curation workflows, incorporating autonomous validation, enrichment, and quality control mechanisms.• Integrated AI agents with Snowflake Cortex for intelligent query generation and analytics automation, enabling seamless interaction between conversational AI and data infrastructure.

EDUCATION

1981 — 1984

Imperial College London

BSc(Eng), Computing Science

2013 — 2016

The University of Manchester

Master of Science (MSc), Digital Biology

1995 — 1997

The University of Manchester

MSc, Software Engineering

2006 — 2009

The Open University

BSc, Life Sciences

SKILLS

Sparx Enterprise ArchitectEnterprise ArchitectureVdmPythonRupArchitecturePl/SqlRJavaPostgresqlComputational BiologyIntegrationHadoopSdlcSolution ArchitectureBioinformaticsOracleRequirements AnalysisBusiness ProcessGenomicsSolarisUnixData ModelingUmlTogafXmlSoaJ2ee Application Development

ABOUT MARK BRUNDRETT

Mark is a software engineer with over 25 years’ experience in the IT industry. He has experience in all phases of the development lifecycle, having delivered projects in many roles including architect, project lead, designer and developer, often leading projects through the complete SDLC from inception to delivery. Mark has both extensive technical expertise and business process/project management experience, gained in a number of industries, such as utilities, government, financial, industrial real-time and aerospace & defence.Mark’s general interests include computer science, cell biology, neuroscience and the space in between (bioinformatics, AI, digital biology, data science/big data). This has driven his move into the genomics space and fueled his interest in optimising the architecture that delivers the value stream from sequence to insight.

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Mark Brundrett — Principal Architect - Strategy & Enterprise at AstraZeneca in Cambridge, GB | Unifers