Mark Rosen
Vice President and Head of Chemistry @Nine Square Therapeutics
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WORK HISTORY
Vice President and Head of Chemistry @Nine Square Therapeutics
CA, US
EDUCATION
UC Irvine
Ph.D., Organic Chemistry
UC San Diego
Bachelor of Science - BS, Chemistry
SKILLS
ABOUT MARK ROSEN
I am a scientist, inventor, and entrepreneur focused on discovering new treatments for ALS, Parkinson\'s disease, and other neurodegenerative diseases. With extensive experience across scientific, business, financial, and operational aspects of biotechnology and pharmaceutical R&D, I am committed to driving the development of innovative therapies that can transform patient outcomes.Key areas of expertise include:Proven Leadership in Pharma R&D: Successfully building and leading high-performing teams to advance pharmaceutical R&D programs, delivering experimental medicines with high clinical potential.Start-Up Growth & Value Creation: Expertise in scaling start-up biotech companies, with a strong focus on identifying and achieving key value inflection points for growth and investment.Entrepreneurial Success: Co-founded a Johnson & Johnson spinout focused on developing novel treatments for inflammatory bowel diseases (IBD) like ulcerative colitis and Crohn’s disease, and played key early roles in other startups.Interdisciplinary Expertise: In-depth knowledge across a range of therapeutic areas and technology platforms, including CNS, immunology, inflammation, metabolic disease, and structure-based drug discovery. Experienced in clinical development, medicinal chemistry, computer-aided drug discovery, molecular biology, and pharmacology.Business Development & Partnerships: Experienced in conducting technology and asset evaluations, presenting R&D programs to potential partners and investors, and managing due diligence processes.Expertise in Drug Discovery: Skilled in driving drug discovery programs across both traditional and non-traditional (e.g,\"undruggable\") targets, including challenging biological target classes.Strong Scientific Foundation: Extensive track record of patents and high-impact publications in leading scientific journals, demonstrating deep expertise in drug discovery and development.Global Network & Collaborative Experience: Strong connections with academic, industrial, and key opinion leader (KOL) networks, with significant experience in managing domestic and international CRO partnerships.
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