Maria I.
Oncology | Biology Lead | Precision Medicine & Biomarker & Data-Driven Drug Discovery | Connecting Patients to the Right Medicine
- Role
- Senior Scientist Ii at Blueprint Medicines
- Location
- Boston, MA, US
- LinkedIn followers
- 500 followers
About Maria I.
My mission is to bridge the gap between complex data and life-changing treatments for patients. As an oncology scientist with over 10 years of industry experience, I am driven by a singular vision: ensuring the right new or repurposed drug reaches the right patient.Currently, I serve as a Biology Lead for Early Drug Discovery Oncology Programs, specializing in well-validated kinase targets and genomically defined cancers. I am passionate about high-quality, data-centric research that reshapes the cancer treatment landscape.Throughout my career, I have thrived in cross-functional teams, advancing programs from target validation through IND-enabling studies. I am always open to connecting with fellow innovators dedicated to precision medicine and patient-focused science.
Experience
Senior Scientist Ii
Feb 2023 — Present · Cambridge, MA, US
Biology Lead of a Targeted Protein Degradation (TPD) program targeting CCNE1-amplified solid tumors, driving progression from lead optimization to Developmental Candidate (DC) nomination in November 2025. The program delivered a best-in-class degrader DC molecule, enabling IND submission and externalization discussions with Sanofi.• Initiated and managed partnerships with CROs in China, India, and Europe, contributing to compound profile characterization (potency, selectivity, toxicity) and mechanism of action (MOA).• Biology Lead of an early discovery campaign (dual approach: small molecule/TPD) with a hematologic target in systemic mastocytosis; led proof-of-concept (POC) experiments required for program nomination, supporting internalization by Sanofi post-acquisition.• Applied molecular and cellular biology techniques, public databases, and computational tools to elucidate MOA and drive programs progression.• Supporting professional development and peer coaching by mentoring direct report and fostering an inclusive, high-performing scientific environment.
Education
University of Patras
PhD, Molecular and Cellular Biology
2004 — 2008
University of Patras
Bachelor’s Degree, Biology
1998 — 2002
Harvard University
Post doctoral appointment, Cancer Biology and Clinical Oncology
2014 — 2016
Bellvitge Biomedical Research Institute
Post doctoral appointment, Cancer Epigenetics and Biology Program
2008 — 2011
University of Patras
Master of Science (M.Sc.), Molecular Biology, Genetics and Cytogenetics
2002 — 2004
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