Margaret Fleming
Senior Director, Translational Science Leader
- Role
- Senior Director, Translational Science Leader Rare Diseases at Ipsen
- Location
- Boston, MA, US
- LinkedIn followers
- 500 followers
About Margaret Fleming
Accomplished R&D translational scientist with extensive drug discovery expertise in pharmaceutical industry across multiple disease indications including inflammatory and autoimmune, respiratory, rare diseases, oncology, and neuroscience-In depth expertise in development of integrated discovery and translational pre-clinical plans-Focus on applying insights from human disease biology (observational cohorts and clinical data) into development of novel therapeutic entities-Project leader of multidisciplinary project teams with track record of bringing NMEs from concept to developmentSpecialties: Innate Immunity and Inflammation, small and large molecule drug discovery, translational research, biomarker plans
Experience
Senior Director, Translational Science Leader Rare Diseases
Nov 2021 — Present · Cambridge, MA, US
Translational biology lead for oncology epigenetics pre-clinical portfolio (multiple assets from lead selection to FIH). Responsible for biology strategy, indication selection and translational plans•Translational research lead for late-stage clinical assets (Palovarotene, Elafibranor, Tazverik). Responsible for disease biology and pharmacology support including non-clinical pharmacology sections for regulatory submissions and biomarker and life cycle management strategies.•Member of IPSEN’s external innovation neuroscience core team. Responsible for due diligence and external opportunity evaluation of assets (early to late stage) through rigorous assessment of preclinical/translational data and delivery of clear recommendations including risk assessment and mitigation plans.
Education
Brandeis University
PHD, biochemistry
University of Miami
Bachelor of Science, Biochemistry
PhD
Doctor of Philosophy (PhD)
Skills
- Biomarkers
- Pharmacology
- Respiratory Disease
- Assay Development
- Drug Development
- Translational Medicine
- Drug Discovery
- Biomarker Discovery
- Inflammation
- In Vitro
- Cell
- Target Identification
- Clinical Development
- Cell Signaling
- Copd
Find verified contacts for anyone on LinkedIn
Unifers gives sales teams verified emails and direct dials, enriched profiles, and outreach that lands in the inbox.
Free plan included · No credit card required
This profile is compiled from publicly available professional sources. Unifers is not affiliated with or endorsed by LinkedIn. Request removal of this profile.