Manoj K. Bhasin

WORK HISTORY

EDUCATION

SKILLS

ABOUT MANOJ K. BHASIN

Dr Manoj K Bhasin has expertise in the Computational Vaccine Design, Functional annotation of proteins, Protein class prediction, gene expression and proteomics analysis that is acknowledged by a solid publication record consisting of more than 35 articles in the international peer reviewed journals. Dr. Bhasin earned the PhD degree in Bioinformatics under the supervision of Dr GPS Raghava from Institute of Microbial Technology INDIA. During Ph.D, he developed two relational databases and many novel algorithms to assist in prediction of potential subunit vaccine candidates using machine learning techniques. Subsequently, he developed interest, in functional annotation and classification of proteins and developed algorithms for subcellular localization of eukaryotic, prokaryotic and specifically human proteins. He developed algorithms for determination and classification of complex proteins families such as GPCRs, Nuclear Receptors. Afterwards, as a postdoctoral Fellow at Dana Farber cancer Institute, he worked on prediction of immunodominat T cell epitopes and methylated CpG in the genomic sequences. In 2006, he was hired by BIDMC Genomics center to lead the Bioinformatics effort. He was also appointed as instructor of Medicine at Harvard Medical School. BIDMC genomics center is a service facility for performing genomics and proteomics experiment. Dr Bhasin provides Bioinformatics support on all the experiments performed at BIDMC Genomics center. He is working on large scale of analysis of cancer gene-expression data to determine the true biological differences in different Cancers, predicting biomarkers and developing cancer prediction models. He is developing a comprehensive package for the large scale analysis of the genomics and proteomics data.Specialties: Gene Expression analysisDevelopment prediction models using ANN and SVMProteomics analysis Biomarker analysis Subunit Vaccine design Functional Annotation of proteins