Maja Sedic

About Maja Sedic

Senior toxicologist and nonclinical development leader with 20+ years of scientific training and professional experience including Cancer Biology, Immunology, and Microbiology. With over a decade of industry experience supporting INDs and early clinical development across multiple therapeutic modalities, including RNA-based therapeutics, biologics, and small molecules. Extensive experience designing, reviewing, and integrating nonclinical safety data to inform regulatory decision-making, first-in-human dose selection, and program risk assessment. Demonstrated scientific and people leadership across toxicology, DMPK, pharmacology, bioanalysis, and pathology functions, with deep familiarity with regulatory expectations for nonclinical packages supporting early-phase clinical development.

Experience

1. VP, Head of Preclinical Research

   Orna Therapeutics

   Nov 2024 — Present · Watertown, MA, US

   Executive oversight of preclinical research functions encompassing toxicology, bioanalysis, DMPK, molecular pathology, and in vivo pharmacology in support of RNA-based therapeutic programs.

Education

• Tufts University

  Doctor of Philosophy (PhD), Cell, Molecular and Developmental Biology

• University of Vermont

  B.S., Genetics and Molecular Biology

Skills

• Senescence
• Microscopy
• Monoclonal Antibodies
• Telomeres
• Chip
• Stem Cell Research
• Transfection
• Cell Biology
• Flow Cytometry
• Cell Culture
• Western Blotting
• Polymerase Chain Reaction (Pcr)
• Multi-Color Flow Cytometry
• Rodent Surgery
• Protein Expression
• Immunofluorescence
• Sirt1
• Molecular Cloning
• Cell Signaling
• Confocal Microscopy
• Gel Electrophoresis
• Pcr
• Immunohistochemistry
• Qpcr
• Cancer Stem Cells
• Brca1
• Real-Time Polymerase Chain Reaction (Qpcr)
• Tissue Culture
• In Situ Hybridization
• Histones
• Dna Damage
• Protein Purification
• Elisa
• Infection
• Genetics
• Immunoprecipitation