Mahsa Yazdani

Computational Biology Co-op at Merck Research Lab, PhD Candidate at UB

Role
Computational Biology Co-op at Merck
Location
San Francisco, CA, US
LinkedIn followers
500 followers

About Mahsa Yazdani

Bioinformatics and spatial multiomics expert skilled in integrating and analyzing complex…

Experience

  1. Computational Biology Co-op

    Merck

    May 2025 — Present · Cambridge, MA, US

    Contributing to the analysis of CRISPR-based Optical Pooled Screening (OPS) data, with a focus on normalization strategies and batch effect correction.• Applying both supervised and unsupervised machine learning techniques to evaluate data quality, optimize feature selection, and identify biologically meaningful patterns.• Benchmarking multiple hit-calling methods to assess sensitivity, specificity, and reproducibility across experimental conditions.• Leveraging deep learning–based Cellpose segmentation model on a specific cell type characterized by heterogeneous, overlapping morphology to enhance single-cell resolution and improve downstream analysis.

Education

  • Shahid Beheshti University of Medical Sciences and Health Services

    Bachelor's degree

    2011 — 2015

  • The State University of New York at Buffalo

    Doctor of Philosophy - PhD

    2021 — 2025

  • University of Tehran

    Master of Science (MS)

    2015 — 2018

  • University of Missouri-Kansas City

    Interdisciplinary Program

    2019 — 2021

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