Daniel Lupu

About Daniel Lupu

With 16 years of experience as a scientist, I have developed expertise in various areas, including clinical development, precision oncology, molecular diagnostics, biomarkers, and translational research:• I conceptualized, designed, and executed clinical development plans and clinical research study protocols for molecular diagnostics and oncology biomarkers studies (5 years) • I led cross-functional teams to execute precision medicine initiatives, integrating molecular, genomic, and clinical data to generate evidence and facilitate enrollment in clinical trials (3 years) • I led scientific and clinical interactions with sponsors to implement Phase 1, 2, and 3 oncology drug development protocols (3 years) • I designed and conducted investigator-initiated translational cancer and cardiovascular genomics studies, as well as oncology Phase IV Real World Evidence and bio-banking registry studies (3 years) • I applied molecular diagnostics expertise to interpret and analyze whole exome sequencing testing data in a production CLIA diagnostics laboratory to determine the clinical relevance of germline and somatic genetic variation in cancer, cardiovascular, and metabolic disorders (2 years).

Experience

1. Director Clinical Research

   Crinetics Pharmaceuticals

   Oct 2024 — Present · San Diego, CA, US

   Develop and gain approval for Clinical Development Plans for three programs: Autosomal Dominant Polycystic Kidney Disease, Obesity and Metabolism (GLP1R agonists/GIP antagonists), and Humoral Hypercalcemia of Malignancy• Lead the design and planning of Phase 1-3 clinical trials• Contribute to Strategic Plans and Target Product Profiles through multidisciplinary consultations• Provide scientific guidance to the biomarkers strategy across multiple programs• Develop relationships with key investigators, opinion leaders, and patient advocates

Education

• The University of North Carolina at Chapel Hill

  Doctor of Philosophy - PhD

• The University of North Carolina at Chapel Hill

  PhD, Nutritional Biochemistry

• Universitatea Transilvania din Brașov

  Doctor of Medicine - MD, Medicine