Lucas Bondurant
- Role
- Senior Scientist at Alnylam Pharmaceuticals
- Location
- Cambridge, MA, US
- LinkedIn followers
- 500 followers
About Lucas Bondurant
Driven research scientist with a passion for mentoring young scientists and developing…
Experience
Senior Scientist
Aug 2021 — Present
Led the identification of siRNA-based Development Candidates with multi-disciplinary teams for numerous metabolic disease programs internally and with external partners Mentored a team of junior scientists on early target discovery projects using RNAi-based strategies to treat metabolic disease in vitro and in vivo Supported IND-enabling and CTA activities for multiple programs Served as PI on rodent and NHP studies with CRO’s in addition to leading internal animal studies Managed and built relationships with external KOL’s Strong track record with on-time delivery of goals, in presentation and in communication skills; thrives in multidisciplinary team structures Developed extensive knowledge and troubleshooting skills with metabolic characterization of rodent and non-human primate disease models with novel therapeutics including but not limited to: Glucose/Insulin Tolerance Tests, MRI-based body fat composition, ex vivo analysis of tissues; as well as common molecular biology techniques including but not limited to: RT-qPCR, ELISA, Western blot, in vitro transfection of plasmids and siRNAs, RNAseq, metabolomics, proteomics and novel protein design using Gibson Assembly Cloning
Education
Missouri State University
Bachelor's Degree, Cell and Molecular Biology
2010 — 2014
University of Iowa
Doctor of Philosophy (Ph.D.), Molecular Medicine
2014 — 2019
La Universidad de Salamanca
Spanish Language and Culture
2012
Skills
- Rna Isolation
- Elisa
- Mammalian Cell Culture
- Molecular Biology
- Mentorship and Education
- Immunoassays
- Western Blotting
- Insulin Tolerance Test
- Metabolic Typing
- Cdna Library Prep
- Flow Cytometry
- Glucose Tolerance Test
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