Lorillee Tallorin
Senior Research Scientist at Vertex Pharmaceuticals
- Role
- Senior Scientist at Vertex Pharmaceuticals
- Location
- Boston, MA, US
- LinkedIn followers
- 500 followers
About Lorillee Tallorin
Ph.D. level scientist -collaborative and motivated chemical biologist/enzymologist with expertise performing small-molecule discovery screens to characterize molecular mechanisms of potential biologic therapeutics. Experience with analysis of protein structure and function, while working with complex biomolecules for characterizing protein and RNA interactions, and understanding enzymatic activity to characterize mechanism of action. Areas of Expertise:• Drug Discovery • Mechanism-of-Action Studies• Natural products • Molecular, Cellular, and Biochemical AssaysSpecialties: Assay Development, biophysical protein characterization, protein-protein interaction, RNA assays, small-molecule inhibitor discovery.Laboratory Skills:Biochemistry & Molecular Biology | Bacterial protein expression • microplate-based enzyme assays • enzymatic absorbance/luminescence/ FRET/alphaLISA/fluorescence-labeling/mass spec/HPLC assays • alpha-screen binding assay • Isothermal Titration Calorimetry (ITC) • Bio-layer interferometry (BLI) • mammalian cell culturing • immunofluorescence microscopy • immunoprecipitation/affinity-pull down • protein purification-size-exclusion/ion-exchange (ÄKTA system) • protein and peptide fluorescent labeling • molecular cloning & PCR • Western blot • liposome mediated transfection• in vitro transcription and translation • RT PCR Chemical Biology | LC-MS • HPLC • FT-IR spectroscopy • UV-Vis Spectroscopy • bottom-up proteomics • peptide synthesis (SPOT array-Intavis) • small molecule probe design for protein • protein interactionSoftware & Computation | GraphPad Prism • ChemDraw • PyMOL • SnapGene/Geneious • Adobe Suite Agilent Mass Hunter LC-MS • ImageJ/Fiji
Experience
Senior Scientist
Feb 2023 — Present · Boston, MA, US
Education
California State University, Los Angeles
Master of Science (M.S.), Chemistry
2008 — 2010
UCLA
Bachelor's Degree, Chemistry
2005 — 2007
Palomar College
Associate's Degree, Chemistry
2003 — 2005
Harvard Medical School
Postdoctoral Fellow, Chemical Biology & Virology
2016 — 2019
UC San Diego
Doctor of Philosophy (PhD), Chemical Biology/Biochemistry
2010 — 2016
Find verified contacts for anyone on LinkedIn
Unifers gives sales teams verified emails and direct dials, enriched profiles, and outreach that lands in the inbox.
Free plan included · No credit card required
This profile is compiled from publicly available professional sources. Unifers is not affiliated with or endorsed by LinkedIn. Request removal of this profile.