Lorenzo Croia
Postdoctoral Scientist @Shenzhen Institutes Of Advanced Technology
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WORK HISTORY
Postdoctoral Scientist @Shenzhen Institutes Of Advanced Technology
Led the development of a novel OMV–liposome hybrid adjuvant platform, coordinating experimental strategy, timelines, and iterative optimization activities within vaccine-oriented projects.• Drove projects targeting HPV, Chikungunya virus, and H5N1 influenza, operating in a translational research environment with potential industrial application.• Actively contributed to IP strategy and patent drafting, resulting in the successful submission of China and PCT patent applications.• Designed and coordinated research plans aligned with downstream applicability, including preclinical validation and technology positioning.• Supported grant writing and project planning, contributing to funding proposals with industrial relevance.• Acted as an interface between scientific data, institutional stakeholders, and external collaborators
EDUCATION
Sapienza Università di Roma
Master's degree, genetics and molecular biology
Sapienza Università di Roma
Bachelor's degree, biology
Università di Trento
PhD in vaccinology and immunology
ABOUT LORENZO CROIA
Experimental PhD skills-MICROBIOLOGY: engineering of bacteria, OMVs isolation and purifications, chemically competent cells preparation, bacterial cultutres, Plasmids construction using the Polymerase Incomplete Primer Extension (PIPE)-IMMUNOLOGY: analysis and optimization of adaptive immune responses, ELISA, ELISpot, Western blotting. Splenocytes, lymph node cells and PBMC isolations from mice and coulture of these cells-IN VIVO EXPERIMENTS: intramuscular, subcutaneous and intraperitoneal immunizations. Mouse surgery. Experimental preDOC skills- TECHNICAL SKILLS IN CELL BIOLOGY, Primary cell culture (PBMC and MSC derived from human bone marrow, and MSC from pig’s bone marrow). Cell lines. MSC, PBMC and CD34+ cells isolation by peripheral/marrow blood with ficoll. Co-culture. Differentiation of MSC in osteoblasts and adipocytes to determine “stem potential”. Freeze cells. MSC seeding in oesophageal scaffold-TECHNICAL SKILLS IN MOLECULAR BIOLOGY: RNA isolation, PCR, cDNA synthesis, quantification and analysis of the RNA integrity, real time RT-PCR- TECHNICAL SKILLS IN HISTOLOGY AND MICROSCOPY: light microscopy, image analysis.
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