Linya Wang

Senior Staff Scientist, Head of Cell Biology @Twist Bioscience

Twist Biopharma devision • Lead multiple immune-oncology and GPCR projects from discovery to lead selection • Design, implement and manage in vitro mechanism of action validation assays (e.g, FACS cell binding, ELISA, cell-based functional assays, primary immune cell assays, cytotoxicity assay, and design in vivo pre-clinical study) • Lead four major projects proceed to pre-clinical phase; One license out to world-leading pharma as the largest revenue project of Twist Biopharma team; Assigned as the project lead of this external project • Effectively and timely communicate scientific interpretation to multi-disciplinary internal departments and external collaborators to deliver quality findings in support of drug candidate advancement • Critical scientific/technical data analysis, experiments interpretation, and report presentation • Establish team structure for lead characterization and stable cell line development workflow • Manage and supervise 5 direct reports including scientists and RAs of Cell Biology team • Validate the potency of bispecific antibodies and secondary ADC cell binding, viability and cytotoxicity assay • Communicate with CRO for in vivo study, metabolic stability assay, PK study, and evaluate new partner collaboration • Listed in 5 patents as an inventor, and 4 paper as an author; Presented in AACR and Keystone symposia as a speaker