Liean S.

About Liean S.

BIOCHEMICAL ENGINEER, PHARMACEUTICAL INDUSTRY LEADER, AND SCIENTIST with strong skill sets in all phases of drug product development and manufacturing,(drug development: biological e.g. Antibodies, Peptides, Small molecules e.g. chemistry synthetic routes, drug formulations). Also, I am adept at Six Sigma principles and data analysis with the ability to produce relevant insights supporting strategic business decisions and long-range program planning. I possess the ability to lead multiple cross-functional teams in a cohesive, strategic direction, while maintaining excellent communications, quality control and compliance.MY CAREER PASSION is blending my biochemical engineering expertise and leadership skills while applying them to the development of scientific projects.CAREER HIGHLIGHTS:• Submission of breakthrough designated Sarcoma treatment within 18 months of clinical data assessment showing an increase in life on 11months; launched within 8 days of US first approval, beat market forecast in sales of commercial supply in first year• Submission of breakthrough designated tumor agnostic cancer treatment with data showing up to 85% objective response rate for patients with RET altered mutations, significantly increasing their survival• Acquisition and Integration of Loxo Oncology and ImClone Systems, bringing new products (4 commercially approved) and drug development capabilities to expand and enhance drug development opportunitiesSKILLS AND EXPERTISE:Pharmaceutical ScientistProgram ManagementProject ManagementTeam LeadershipEarly Phase DevelopmentPortfolio ManagementCommercial LaunchMentor / CoachLate Phase DevelopmentNegotiation / InfluenceProcess DevelopmentSupervision / SMEAsset Due DiligenceContract AnalysisKey StakeholdersRisk ManagementVC Partnership RelationsGovernanceVendor SelectionAcquisitionsContinuous ImprovementSix Sigma Green BeltCMO OversightDrug DevelopmentBudget ManagementExternal Asset AnalysisIn-license ProductsStrategic Direction

Experience

1. Senior Vice President, Head of Cmc

   Acumen Pharmaceuticals, Inc

   Feb 2025 — Present · US

Education

• UCL

  Msc, Biochemical Engineering

  1996 — 1997

• University of Kent

  Bsc, Microbiology

  1992 — 1996

Skills

• Glp
• Biochemistry
• R&D
• Biochemical Engineering
• Downstream Processing
• Monoclonal Antibodies
• Pharmaceutical Industry
• Sop
• Fda
• Cell Culture
• Regulatory Affairs
• Lifesciences
• Purification
• Gmp
• Regulatory Submissions
• Chromatography
• Life Sciences
• Molecular Biology
• Biosimilars
• Elisa
• Protein Chemistry
• Cmc
• Ind
• Drug Discovery
• Clinical Development
• Contract Manufacturing
• Fermentation
• Validation
• Hplc
• Analytical Chemistry
• U.s. Food and Drug Administration (Fda)
• Cell
• Mammalian Cell Culture
• Gxp
• Aseptic Processing
• Chemistry
• Technology Transfer
• CRO
• Commercialization
• Biotechnology