Léa Rochet
Conjugation Scientist @ADC Therapeutics
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WORK HISTORY
Conjugation Scientist @ADC Therapeutics
London, GB
Synthesized antibody-drug conjugates (ADCs) using a broad range of conjugation chemistries and diverse cytotoxic payloads to support different projects under a strict timeline.• Purified and characterized ADCs using analytical techniques such as HIC, SEC, PLRP, UV, and LC-MS.• Contributed to the development of novel ADC formats.• Assessed the stability and efficacy of linker-payload, and design of new linker-payload when necessary.• Developed and implemented new conjugation strategies aimed to broaden the company toolbox which were applied to different projects.• Managed and maintained HPLC systems, ensuring method development, troubleshooting, and routine analysis were performed efficiently.• Led a project focused on the development of a novel drug class for ADC applications, managed a cross-functional team and reported monthly to the leadership team.• Collaborated cross-functionally with protein production, protein purification and bioassay teams to support ADC pipeline progression.
EDUCATION
Université de Montréal
Chimie
CPE Lyon
Diplôme d'ingénieur, Chimie
UCL
Doctor of Philosophy - PhD, Chemical Biology
ABOUT LÉA ROCHET
Conjugation scientist with a strong background in Antibody-Drug Conjugates (ADC) spanning both academia and industry, where I’ve led and contributed to cutting-edge projects focused on developing novel ADC therapies. My expertise covers the full spectrum of ADC development - from the production and engineering of conjugatable platform to bioconjugation technology development, payload-linker design optimization and synthesis and safe handling of high-potency compounds.Over the years, I’ve had the privilege of learning from and working alongside some of the top experts in the field, which has shaped my scientific approach and fuelled my drive to innovate. I’m passionate about advancing the next generation of ADCs and bringing meaningful therapies to patients. I thrive in collaborative, mission-driven environments where scientific excellence and impact go hand in hand.
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