Laura Silvian
- Role
- Senior Director at Biogen
- Location
- Cambridge, MA, US
- LinkedIn followers
- 500 followers
About Laura Silvian
Drug Hunter developing protein and small molecule therapeutics through structure-based…
Experience
Senior Director
Jun 2019 — Present
Responsible for defining and managing priorities, resources and investments in structure-based drug design at Biogen. Contribute to the growth and development of staff, mentoring and motivating scientists-Define strategy to utilize structure-based rational design to enhance the speed and efficiency of the discovery pipeline (NMR, Crystallography, CryoEM)-Use protein sciences and biophysics techniques for small molecule hit finding, SAR and interpretation of MOA-Working knowledge of biochemical and cell-based assay development and screening to enable small molecule target discovery -Broad understanding of small molecule drug discovery pipeline including project leadership experience for 3 preclinical programs. Strong collaborative skills working internally and externally towards execution of projects through assay development, leadID, LeadOP and into IND studies.
Education
Yale University
Ph.D., Molecular Biophysics and Biochemistry
1991 — 1998
Harvard Medical School
Biological Chemistry and Molecular Pharmacology
1998 — 2002
University of Chicago
S.B., Biochemistry
1987 — 1991
Skills
- Biophysical Chemistry
- Antibodies
- X-Ray Crystallography
- Protein Purification
- Protein Structure
- Protein-Protein Interactions
- Protein Expression
- Protein Chemistry
- Purification
- Biochemistry
- Drug Discovery
- Drug Design
- Structural Biology
- Nmr
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