Laura Bordone

Director Clinical Development @Ionis Pharmaceuticals, Inc.

San Diego County, CA, US
MOBILE NUMBERS
+16•••••••16

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WORK HISTORY

Jun 2023 — Present

Director Clinical Development @Ionis Pharmaceuticals, Inc.

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Carlsbad, CA, US

Global Program Team Leader for donidalorsen (Dawnzera), an RNA-based therapeutic for hereditary angioedema (HAE):• Directed the global development strategy from early clinical phases through late-stage trials, achieving FDA approval on August 21, 2025• Provide strategic oversight of global clinical programs, including study design, execution, and data evaluation to ensure safety, efficacy, and regulatory readiness• Lead cross-functional collaboration across clinical operations, regulatory affairs, medical affairs, and commercial teams, serving as a key supporting partner for clinical and regulatory functions• Partner with investigators, CROs, and vendors to deliver high-quality clinical data and operational outcomes• Guide and support global regulatory submissions (NDA, CSRs, IB, PIP, ODD) and scientific communications, including publications, abstracts, and conference presentations• Core member of IonisNEXT ERG, engaging students in STEM education and mentoring future leaders in science

EDUCATION

2002 — 2005

Massachusetts Institute of Technology

Postdoctoral fellow

1998 — 2002

University of Minnesota

PhD, Pharmacology

1989 — 1993

Università degli Studi di Milano

Laurea, Biology

2014

BIOCOM Institute

BioCollaborative Life Science Immersion Program, BRIDGE Grant

SKILLS

ImmunologyAssay DevelopmentOncologyRegenerative MedicineLife SciencesLaboratoryDrug DevelopmentCell Based AssaysValidationScienceBiochemistryLifesciencesBiomarkersHigh Throughput ScreeningPharmacologyCell CultureResearchBiotechnologyDrug DiscoveryLead OptimisationCell BiologySmall MoleculesHit-to-LeadMetabolismBiomarker DiscoveryMolecular BiologyBiotherapeuticsInflammationPharmaceutical IndustryIn VitroTarget IdentificationCell

ABOUT LAURA BORDONE

Pharmaceutical leader with proven expertise in clinical drug development and global program leadership. Successfully led donidalorsen (Dawnzera) from Phase 2 through FDA approval and currently serve as Global Program Team Leader, driving strategy and execution in late-stage development for hereditary angioedema (HAE).

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