Kuntal de

About Kuntal de

I\'m a research scientist and biochemist with extensive experience in oncology, microbiology, biotechnology, and molecular research. I\'ve worked in clinical settings using small molecule inhibitors and have been involved in the development of novel therapeutic targets. I\'ve discovered a domain in oncogenic protein that can be targeted to block the cancer pathway and identified novel pathway to stop the viral entry and replication of SARS CoV-2. I approach goals and tasks with conscientiousness, exacting detail, and have made significant contributions. Email: k••••••••@gmail.com Contact:51••••••76 Key Achievements: •Identified two small molecule inhibitors, proTAME and apcin, that show promising results against radioresistant and therapeutic resistant brain cancer GBM stem cells. These findings have helped the lab to publish 2 research articles and secure an grant from the American Cancer Society. •New COVID-19 pathway discovered to stop viral entry and replication and novel protein domain found in oncogenic protein can be targeted to block cancer pathway. •Created a new platform for Bioscience division, including research on human cell lines & expression systems, resulting in 2 patents & 4 publications that received media attention. • Helped in securing $9M SEED funding through DOE review from 20••••26. • Supervised 14 junior researchers and 60 undergrads in teaching labs for 4 years at a top-ranked school. Core Expertise- Leadership and Management - Multidiscipline Collaboration - Biochemical, In-Vivo and In-Vitro Assays - Cell Based Assays and incuCyte -Live Imaging Microscopy -CRISPR Technology -Confocal Microscopy and EM - DNA/RNA Purification/Isolation - Primer Design, Cloning - Protein Expression and Purification (E.coli and Mammalian)- ShRNA and siRNA - Microbiological Techniques - Biosafety Level 2 (BSL-2) Techniques - Co-Immunoprecipitation and ChIP As someone skilled in a variety of microscopic techniques, and a holder of doctoral degree in biochemistry, my passion is to apply biomedical science to uncover vital information and impact methodologies for improving human health. Please contact me at k••••••••@gmail.com to find out how I might contribute and add value to your organization.

Experience

1. Staff

   Oak Ridge National Laboratory

   Oct 2022 — Present · Oak Ridge, TN, US

   Oak Ridge National Laboratory delivers scientific discoveries and technical breakthroughs through impactful research and world-leading research centers. Partnerships include other laboratories and programs, universities, and industry allowing Oak Ridge National Laboratory to pair strengths with others for outstanding contributions to science.• Started new system and successfully grow and maintain cell lines, including the clinical expression systems U87MG, HCT116, and HeLa.• Identified a novel pathway to stop the viral entry and replication of COVID-19 which will help in fighting variants• Work with multidisciplinary departments and researchers including Microbiology and Computational Biologists.• Discovered novel protein domain in oncogenic protein which can be targeted to block cancer pathway.• 3 scientific publications, 3 presentations, 1 US Patent and 1 article review

Education

• Miami University

  Doctor of Philosophy - PhD