Kirill Nadezhdin
Senior Scientist @AstraZeneca
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WORK HISTORY
Senior Scientist @AstraZeneca
Gaithersburg, MD, US
EDUCATION
Moscow Institute of Physics and Technology (State University) (MIPT)
Bachelor of Applied Science - BASc
Lomonosov Moscow State University (MSU)
Doctor of Philosophy - PhD
Moscow Institute of Physics and Technology (State University) (MIPT)
Master's degree
Columbia University
Postgraduate Degree
ABOUT KIRILL NADEZHDIN
Accomplished biomedical research scientist with >15 years of experience in protein biochemistry, structural biology, and biophysics. I am interested in applying my expertise to investigate complex biological systems, uncover underlying molecular mechanisms of action, and facilitate structure-based drug design (SBDD). Some notable achievements during my postdoctoral training include- Designing >100 constructs for cryo-EM, successfully expressing and purifying more than 10 proteins, leading to the publication of >10 articles in top-ranked peer-reviewed journals- Optimizing protein purification protocols resulting in reduction of over 50% in purification time and cost, while maintaining the same yield- Successfully solving cryo-EM structures of membrane proteins in complex >15 small molecules and protein-based binding partners- Discovering the fundamental structural mechanism through which temperature-sensitive ion channel proteins sense heat. I am enthusiastic about collaborating with highly creative individuals to design research pipelines to develop novel methods for exploring molecular mechanisms and discovering new drugs to treat age, environment, and genetics-related diseases. Additionally, I like using data analysis and Python coding skills to streamline time-consuming repetitive tasks, allowing more time for testing innovative ideas. Outside of work, I enjoy engaging in sports, exploring diverse cuisines, and learning new languages. I love building new connections, so feel free to connect with me on LinkedIn
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