Santosh Karki
Development Scientist, Protein Characterization at Alexion Pharmaceuticals, Inc.
- Role
- Development Scientist Iii, Protein Characterization at Alexion Pharmaceuticals, Inc.
- Location
- Philadelphia, PA, US
- LinkedIn followers
- 500 followers
About Santosh Karki
Experienced Analytical Scientist skilled in TOF-MS, Ion mobility mass spectrometry, Liquid Chromatography-Mass Spectrometry (LC-MS), MALDI-TOF, HILIC, etc.Strong research professional with a Doctor of Philosophy - PhD focused in femtosceond laser ablation coupled with electrospray ionization mass spectrometry for structural analysis of bio-molecules. Postdoctoral training focused in the development/commercialization of multi-functional automated platform geared towards biological application. Current work involves the development of novel BioTherapeutics via Early Phase Peptide-mapping/Protein Characterization (PTMs, Sequence variance, etc.), oligosaccharide mapping using HILIC.
Experience
Development Scientist Iii, Protein Characterization
Mar 2025 — Present · New Haven, CT, US
Education
Central Department of Chemistry, Tribhuvan University, Nepal
MSc, Inorganic Chemistry
Temple University
Doctor of Philosophy - PhD, Analytical Chemistry
Skills
- Uv/Vis Spectroscopy
- Synapt G2-Si Hdms
- Public Speaking
- Q-Tof
- Microsoft Office
- Research
- Liquid Chromatography-Mass Spectrometry (Lc-Ms)
- Protein Structure
- Management
- Data Analysis
- Ion Mobility Mass Spectrometry
- Uv-Vis Spectroscopy
- Mass Spectrometry
- Teaching
- Circular Dichroism
- Matrix-Assisted Inlet Ionization (Maii)
- Matrix Assisted Laser Desorption Ionization (Maldi)
- Analytical Chemistry
- Electrospray Ionization Mass Spectrometry
- Electrospray
- Microsoft Word
- Tof-Ms
- Ni Labview
- High-Performance Liquid Chromatography (Hplc)
- Quantification
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