Karin Reif

Senior Director | Program Leader | Owner KARBio LLC

Role
Senior Director, Translational Medicine at TRexBio
Location
South San Francisco, CA, US
LinkedIn followers
500 followers

About Karin Reif

As a research scientist with 20+ years drug discovery and development experience, I am passionate about guiding research and cross-functional teams to identify and characterize new drug candidates for unmet needs. As a director, independent consultant, and project team leader, I designed research plans, developed screening assay cascades, and identified biomarkers to develop novel biologics and small molecule drugs. I contributed or directly advanced >10 drug candidates to late-stage research or early development including 4 to Phase I clinical trials across multiple therapeutic areas (inflammation, asthma, and oncology). I authored or co-authored approved INDs, Investigator’s Brochures, 3 patent applications, and 42 scientific publications. I am passionate about designing original assays and research plans that are guided by target biology and that connect drug candidate mechanism of action to disease pathway activity. • Translational research • Team management • Project management • Drug development • Target validation • Assay development • Biomarker discovery • IND Filing

Experience

  1. Senior Director, Translational Medicine

    TRexBio

    Dec 2025 — Present · South San Francisco, CA, US

    Program Leader | Head of Screening Assay Development

Education

  • UCL

    Doctor of Philosophy (Ph.D.), Biochemistry, Immunology

    1997

  • Freie Universität Berlin

    Diploma (M.Sc.), Biochemistry, Immunology, Biophysics

    1992

Skills

  • Immunology
  • Drug Discovery
  • Biotechnology
  • Molecular Biology
  • Cell Biology
  • Drug Development
  • Flow Cytometry
  • Biochemistry
  • Assay Development
  • Cell Culture
  • Cell
  • Oncology
  • Biomarker Discovery
  • Tumor Immunology
  • Hematologic Malignancies
  • Research
  • Protein Chemistry
  • Cell Based Assays
  • Elisa
  • Project Team Management

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Karin Reif — Senior Director, Translational Medicine at TRexBio in South San Francisco, CA, US | Unifers