Kamal Asadipour
Postdoctoral Scientist @Cedars-Sinai
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WORK HISTORY
Postdoctoral Scientist @Cedars-Sinai
Los Angeles, CA, US
Research Project 1: Lead research on T cell activation and exhaustion mechanisms in triple-negative breast cancer (TNBC) following Pembrolizumab–radiation (RT) combination therapy, utilizing single-cell RNA sequencing (scRNA-seq), single-cell TCR sequencing (scTCR-seq), and flow cytometry for comprehensive immune profiling.• Research project 2: Conduct studies on neuro-immune interactions in TNBC, examining the role of nociceptor-derived CGRP–CRLR/RAMP1 signaling in modulating T cell exhaustion within the tumor microenvironment post-combination therapy.
EDUCATION
Old Dominion University
Ph.D., Biomedical Engineering
Islamic Azad University, Science And Research Branch
Bachelor's degree, Biomedical Engineering
Semnan University
Master's degree, Biomedical Engineering
ABOUT KAMAL ASADIPOUR
Immuno-oncology researcher with strong expertise in tumor immunology, radiation biology, and single-cell technologies. Experienced in leading preclinical studies on T cell activation, exhaustion, and neuro-immune crosstalk in solid tumors, including triple-negative breast, melanoma and gastric cancer. Proficient in single-cell RNA and TCR sequencing, multi-parameter flow cytometry, and molecular pathway analysis (alarmin signaling, apoptosis, pyroptosis). Background includes developing patented nanosecond pulsed electric field (nsPEF) technologies for cancer ablation and immune activation. Proven ability to integrate in vivo models, multi-omics data, and translational immunotherapy research.TECHNICAL SKILLS:Genomics & Single-Cell Technologies: Single-cell RNA sequencing (scRNA-seq), single-cell TCR sequencing (scTCR-seq), data analysis with Cell Ranger and Seurat.Molecular & Cellular Biology: Cell culture, aseptic techniques, multi-parameter flow cytometry (analysis & sorting), immune cell isolation, protein purification, transfection, Western blot, ELISA, qPCR/RT-PCR, gel electrophoresis, CRISPR/Cas9 gene editing, Seahorse XF, Oxygraph mitochondrial assays.In Vivo Models: Murine handling and tumor implantation (breast, melanoma, gastric, liver), IV/IP/SC injections, blood collection, tissue harvesting, IVIS imaging, gene electrotransfer, specimen processing.Data Analysis & Software: FlowJo, GraphPad Prism, ImageJ, Microsoft Office Suite; basic programming in R, Python, and C++.Material Characterization: Biomaterial synthesis and scaffold fabrication; FTIR, ICP, SEM/TEM, XRD, BET analyses.
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