Julien Roth

Senior Scientist @Genentech

Redwood City, CA, US
EMAILS
r••••••••@gene.com
MOBILE NUMBERS
+16•••••••27

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WORK HISTORY

Dec 2023 — Present

Senior Scientist @Genentech

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South San Francisco, CA, US

Complex in Vitro Systems Group | Safety Assessment- Initiated and leading efforts to create predictive 3D models of human neurotoxicity with automated organoid culture and characterization- Developing three-dimensional in vitro models of the human blood brain barrier with microfluidics and brain-mimetic biomaterials- Collaborating across Research and Early Development to integrate machine learning algorithms into analysis of neurophysiological data

EDUCATION

N/A

UC San Diego

Bachelor's Degree, Physiology and Neuroscience (B.S.) | Psychology (B.S.)

N/A

Stanford University

Doctor of Philosophy, Stem Cell Biology and Regenerative Medicine (Ph.D.)

ABOUT JULIEN ROTH

I am Senior Scientist at Genentech working within Safety Assessment to develop novel in vitro models of human neural tissues. The successful creation and implementation of these models requires advances from a range of fields, including stem cell neurobiology, biomaterials, microfluidics, and automation, to come together synergistically. Prior to starting at Genentech, I worked at the interface between bioengineering, computational biology, and stem cell biology to create biomimetic models of human brain development and disease. I leveraged techniques including hiPSC differentiation, neural organoid fabrication, 3D bioprinting, biomaterials engineering, and next generation sequencing. I also developed new approaches and platforms within the tissue engineering field and am included as an author/inventor in several manuscripts/patents describing their application.

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